Influenza A virus (IAV) is a significant human pathogen causing annual epidemics and
periodic pandemics. CD8+ cytotoxic T lymphocyte (CTL)-mediated immunity contributes to …

The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live
poultry markets. It has caused infections in humans in China since 2013. Five waves of the …

Compared to adults, infants suffer higher rates of hospitalization, severe clinical
complications, and mortality due to influenza infection. We found that γδ T cells protected …

Influenza is a major global health problem, causing infections of the respiratory tract, often
leading to acute pneumonia, life-threatening complications and even deaths. Over the last …

CD 4 T cells convey a number of discrete functions to protective immunity to influenza, a
complexity that distinguishes this arm of adaptive immunity from B cells and CD 8 T cells …

Influenza viruses cause a significant amount of morbidity and mortality. Understanding host
immune control efficacy and how different factors influence lung injury and disease severity …

Influenza A virus is highly contagious, infecting 5–15% of the global population every year. It
causes significant morbidity and mortality, particularly among immunocompromised and at …

Avian influenza viruses (AIVs) circulate naturally in wild aquatic birds, infect domestic
poultry, and are capable of causing sporadic bird-to-human transmissions. AIVs capable of …

Analysis of pre-existing immunity and its effects on acute infection often focus on memory
responses associated with a prior infectious exposure. However, memory responses occur …

Influenza virus frequently mutates due to its error-prone polymerase. This feature contributes
to influenza virus's ability to evade pre-existing immunity, leading to annual epidemics and …