NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer
LL Coutinho, EL Femino, AL Gonzalez… - International Journal of …, 2024 - mdpi.com
Nitric oxide (NO) and reactive nitrogen species (RNS) exert profound biological impacts
dictated by their chemistry. Understanding their spatial distribution is essential for …
dictated by their chemistry. Understanding their spatial distribution is essential for …
Examining hemin and its derivatives: induction of heme-oxygenase-1 activity and oxidative stress in breast cancer cells through collaborative experimental analysis …
AM Alsharabasy, PI Lagarias… - Journal of Medicinal …, 2024 - ACS Publications
Hemin triggers intracellular reactive oxygen species (ROS) accumulation and enhances
heme oxygenase-1 (HOX-1) activity, indicating its potential as an anticancer agent, though …
heme oxygenase-1 (HOX-1) activity, indicating its potential as an anticancer agent, though …
Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer
V Consoli, V Sorrenti, M Gulisano… - Molecular and Cellular …, 2024 - Springer
Breast cancer remains a significant global health challenge, with diverse subtypes and
complex molecular mechanisms underlying its development and progression. This review …
complex molecular mechanisms underlying its development and progression. This review …
Facile Synthesis of Hemin Derivatives with Modulated Aggregation Behaviour and Enhanced Nitric‐Oxide Scavenging Properties as New Therapeutics for Breast …
Nitric oxide (• NO) plays various pathophysiological roles in breast cancer, significantly
influencing the migration of tumour cells through concentration gradients. Therefore …
influencing the migration of tumour cells through concentration gradients. Therefore …
Hemin as a Molecular Probe for Nitric Oxide Detection in Physiological Solutions: Experimental and Theoretical Assessment
Given its pivotal role in modulating various pathological processes, precise measurement of
nitric oxide (● NO) levels in physiological solutions is imperative. The key techniques …
nitric oxide (● NO) levels in physiological solutions is imperative. The key techniques …
Engineering hemin-loaded hyaluronan needle-like microparticles with photoprotective properties against UV-induced tissue damage
This study aimed to develop hyaluronan (HA)-based hydrogel microparticles (MPs) loaded
with hemin to address the limitations of traditional macroscale hydrogels. The objective is to …
with hemin to address the limitations of traditional macroscale hydrogels. The objective is to …
Loss of ST3GAL4 exhibits an anticancer effect in breast cancer via the glycolysis pathway
X Chen, C Ren, Z Zhou, J Chen, X Fan… - Biomedical …, 2023 - spandidos-publications.com
Sialyltransferases responsible for glycoprotein sialylation are key regulators in cancer
progression. Although ST3 β‑galactoside α‑2, 3‑sialyltransferase 4 (ST3GAL4), an important …
progression. Although ST3 β‑galactoside α‑2, 3‑sialyltransferase 4 (ST3GAL4), an important …
[HTML][HTML] Role of hemolysis on pulmonary arterial compliance and right ventricular systolic function after cardiopulmonary bypass
Background Cardiopulmonary bypass (CPB) is associated with intravascular hemolysis
which depletes endogenous nitric oxide (NO). The impact of hemolysis on pulmonary …
which depletes endogenous nitric oxide (NO). The impact of hemolysis on pulmonary …
Development of a 3D printed liquid-core hydrogel platform for real-time carbon nanotube sensors
Due to bioprinting technologies using a comparatively small amount of material, especially
those that use print-on-demand techniques, they are considered to be promising production …
those that use print-on-demand techniques, they are considered to be promising production …