CJ Straub, LE Rusali, KM Kremiller… - Journal of medicinal …, 2022 - ACS Publications
For decades, ibogaine─ the main psychoactive alkaloid found in Tabernanthe iboga─ has been investigated as a possible treatment for substance use disorders (SUDs) due to its …
Mecamylamine (3-methylaminoisocamphane hydrochloride) is a nicotinic parasympathetic ganglionic blocker, originally utilized as a therapeutic agent to treat hypertension …
X Wang, JM McIntosh, MM Rich - Journal of Neuroscience, 2018 - Soc Neuroscience
Block of neurotransmitter receptors at the neuromuscular junction (NMJ) has been shown to trigger upregulation of the number of synaptic vesicles released (quantal content, QC), a …
Acetylcholine (ACh), released from axonal terminals of motor neurons in neuromuscular junctions regulates the efficacy of neurotransmission through activation of presynaptic …
Nicotine addiction and other forms of drug addiction continue to be significant public health problems in the United States and the rest of the world. Accumulated evidence indicates that …