Cancer poses a severe threat to human health. Although conventional chemotherapy
remains a cornerstone of cancer treatment, its significant side effects and the growing issue …

Nisin, a typical lantibiotic, has robust antimicrobial activity combined with limited cytotoxicity,
and the development of resistance to it is slow. These properties make nisin a promising …

The great variability of cancer types demands novel drugs with broad spectrum, this is the
case of Nisin, a polycyclic antibacterial peptide that recently has been considered for …

Multidrug resistance (MDR) is a major obstacle in the therapy of infectious diseases and
cancer. One of the major mechanisms of MDR is the overexpression of efflux pumps (EPs) …

Nisin, a small antimicrobial peptide, has been recently suggested as a novel potential
therapeutic approach to treat cancer with no toxicity in humans. The current study used cross …

Modern cancer diagnostics and treatment options have greatly improved survival rates; the
illness remains a major cause of mortality worldwide. Current treatments for cancer, such as …

The global concern over the emergence of antibiotic-resistant pathogens is growing,
demanding for new and more effective antimicrobial strategies. Antimicrobial peptides …

The bacteriocin, nisin, produced by Lactococcus and Streptococcus species during
fermentation, is widely used for bio preservatives in a wide variety of foods. Liver cancer has …

This study was focused on the action of lantibiotic nisin on the phospholipid membranes.
Nisin did not produce ion-permeable pores in the membranes composed of DOPC or DOPE …

Background: For many years, the chemotherapeutic agent doxorubicin (DOX) has been
used to treat various cancers; however, DOX initiates several critical adverse effects. Many …