The identification of actionable tumor antigens is indispensable for the development of
several cancer immunotherapies, including T cell receptor–transduced T cells and patient …

The myriad of peptides presented at the cell surface by class I and class II major
histocompatibility complex (MHC) molecules are referred to as the immunopeptidome and …

Despite the availability of major histocompatibility complex (MHC)-binding peptide
prediction algorithms, the development of T-cell vaccines against pathogen and tumor …

There is an increasing need in biology and clinical medicine to robustly and reliably
measure tens to hundreds of peptides and proteins in clinical and biological samples with …

Highlights•Immunopeptidomics analysis reveals the in vivo antigenic repertoire of
tumors.•Shared cancer antigens and private neo-epitopes are detected by …

Peptides bound to class I major histocompatibility complexes (MHC) play a critical role in
immune cell recognition and can trigger an antitumor immune response in cancer. Surface …

Current knowledge about the dynamics of antigen presentation to T cells during viral
infection is very poor despite being of fundamental importance to our understanding of anti …

Objective The association of HLA–B27 with spondyloarthropathy is one of the strongest
documented for any autoimmune disease. A common hypothesis for this association is the …

Peptides presented by human leukocyte antigen (HLA) molecules on the cell surface play a
crucial role in adaptive immunology, mediating the communication between T cells and …

Glioblastoma multiforme (GBM) is the most aggressive brain tumor with poor prognosis to
most patients. Immunotherapy of GBM is a potentially beneficial treatment option, whose …