Astrocytes can serve multiple functions in maintaining cellular homeostasis of the central
nervous system (CNS), and normal functions for autophagy in astrocytes is considered to …

Neurological diseases are multifactorial, devastating diseases that are causative for various
neurodegenerative disorders. Emerging evidence points that accumulation of unfolded …

Objectives Neuropathic pain (NP) represents a broad scope of various pathological
ramifications of the nervous system. Remimazolam is a proved sedative in treating …

Autophagy has emerged as an integral part of the antiviral innate immune defenses,
targeting viruses or their components for lysosomal degradation. Thus, successful viruses …

Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of cellular
proliferation and survival which controls cellular response to different stresses, including …

There are numerous types of pathological changes in human immunodeficiency virus (HIV)-
associated neurocognitive disorder (HAND), including apoptosis of neurons. HIV-1 …

HIV‐1‐associated neurocognitive disorders (HAND) are a major concern in HIV‐infected
individuals despite the currently available antiretroviral therapy regime. Impaired M1 pro …

Although antiretroviral therapy (ART) affects virologic suppression and prolongs life
expectancies among HIV-positive patients; HIV-1-associated neurocognitive disorders …

Simple Summary Glioblastoma (GBM) is the most common and aggressive brain tumor with
an incidence rate of nearly 3.19/100,000. Current therapeutic options fall short in improving …

In the era of combined antiretroviral therapy (cART), HIV-1 infection has transformed from a
death sentence to a manageable, chronic disease. Although the life expectancy of HIV+ …