Voltage-gated sodium channels (VGSCs) initiate action potentials in electrically excitable
cells and tissues. Surprisingly, some VGSC genes are aberrantly expressed in a variety of …

Introduction: Cardiovascular disease remains the commonest health problem in developed
countries, and residual risk after implementing all current therapies is still high. The use of …

The emergence of OpenAI's ChatGPT has put intense spotlight on Generative AI (Gen-AI)
systems and their possible impacts on Academic integrity. This paper provides an overview …

Dysregulated lipid metabolism is a prominent feature of prostate cancer that is driven by
androgen receptor (AR) signaling. Here we used quantitative mass spectrometry to define …

The concentration of sodium ions (Na+) is raised in solid tumours and can be measured at
the cellular, tissue and patient levels. At the cellular level, the Na+ gradient across the …

Voltage-gated sodium channels (NaV) are molecular characteristics of excitable cells. Their
activation, triggered by membrane depolarization, generates transient sodium currents that …

Ion channels are key regulators of cancer cell pathophysiology. They contribute to a variety
of processes such as maintenance of cellular osmolarity and membrane potential, motility …

The present invention relates to, inter alia, pharmaceutical compositions comprising EPA
and one or more cardiovascular agents, and to therapeutic methods for treating various …

The organic construct consumed as food comes packaged in units that carry the active
components and protect the entrapped active materials until delivered to targeted human …

This study is to investigate the role of Nrf2 in suppressing LPS-mediated inflammation in ex
vivo macrophages by polyunsaturated fatty acids (PUFA) docosahexaenoic acid (DHA) and …