Drug-induced kidney stones and crystalline nephropathy: pathophysiology, prevention and treatment

M Daudon, V Frochot, D Bazin, P Jungers - Drugs, 2018 - Springer
Abstract Drug-induced calculi represent 1–2% of all renal calculi. The drugs reported to
produce calculi may be divided into two groups. The first one includes poorly soluble drugs …

Apatite biominerals

C Combes, S Cazalbou, C Rey - Minerals, 2016 - mdpi.com
Calcium phosphate apatites offer outstanding biological adaptability that can be attributed to
their specific physico-chemical and structural properties. The aim of this review is to …

Renal struvite stones—pathogenesis, microbiology, and management strategies

R Flannigan, WH Choy, B Chew, D Lange - Nature reviews Urology, 2014 - nature.com
Infection stones—which account for 10–15% of all urinary calculi—are thought to form in the
presence of urease-producing bacteria. These calculi can cause significant morbidity and …

Multiple pathways for pathological calcification in the human body

N Vidavsky, JAMR Kunitake… - Advanced healthcare …, 2021 - Wiley Online Library
Biomineralization of skeletal components (eg, bone and teeth) is generally accepted to
occur under strict cellular regulation, leading to mineral–organic composites with …

Current insights into the mechanisms and management of infection stones

EJ Espinosa-Ortiz, BH Eisner, D Lange… - Nature Reviews …, 2019 - nature.com
Infection stones are complex aggregates of crystals amalgamated in an organic matrix that
are strictly associated with urinary tract infections. The management of patients who form …

Molecular imposters functioning as versatile growth modifiers of urate crystallization

W Tang, C Smith, CB Parry, J Meegan… - Crystal Growth & …, 2023 - ACS Publications
Interactions between molecular modifiers and crystal surfaces govern numerous processes
and structural outcomes of natural, biological, and synthetic crystallization. An efficient …

Kidney stone analysis techniques and the role of major and trace elements on their pathogenesis: a review

VK Singh, PK Rai - Biophysical reviews, 2014 - Springer
Kidney stone disease is a polygenic and multifactorial disorder with a worldwide distribution,
and its incidence and prevalence are increasing. Although significant progress has been …

Stage-specific and location-specific cartilage calcification in osteoarthritis development

X Wang, Q Wu, R Zhang, Z Fan, W Li, R Mao… - Annals of the …, 2023 - ard.bmj.com
Objectives This study investigated the stage-specific and location-specific deposition and
characteristics of minerals in human osteoarthritis (OA) cartilages via multiple nano …

Nanoscale analysis of Randall's plaques by electron energy loss spectromicroscopy: insight in early biomineral formation in human kidney

C Gay, E Letavernier, MC Verpont, M Walls, D Bazin… - ACS …, 2020 - ACS Publications
Idiopathic kidney stones originate mainly from calcium phosphate deposits at the tip of renal
papillae, known as Randall's plaques (RPs), also detected in most human kidneys without …

[HTML][HTML] Whitlockite structures in kidney stones indicate infectious origin: a scanning electron microscopy and Synchrotron Radiation investigation

D Bazin, RJ Papoular, E Elkaim… - Comptes …, 2022 - comptes-rendus.academie-sciences …
In this contribution dedicated to kidney stones containing Whitlockite (Wk), we addressed
three questions, namely, the presence of iron in Wk, the relationship between bacterial …