Radiotherapy is an important component of cancer treatment, with approximately 50% of all
cancer patients receiving radiation therapy during their course of illness. Nevertheless, solid …

Simple Summary Accumulating evidence indicates that hypoxia-inducible factor-1 (HIF-1)
plays a pivotal role in tumor biology, particularly in hypoxic environments. Over the past few …

Despite the advances in cancer treatment in recent years, the development of resistance to
cancer therapy remains the biggest hurdle towards curative cancer treatments. Therefore …

MicroRNAs (miRNAs) are short (18–25 nt), non-coding, widely conserved RNA molecules
responsible for regulating gene expression via sequence-specific post-transcriptional …

Radiotherapy (RT) is considered as a standard in the treatment of most solid cancers,
including glioblastoma, lung, breast, rectal, prostate, colorectal, cervical, esophageal, and …

Background Although immune checkpoint blockade (ICB) has been proven to achieve a
persistent therapeutic response in various tumor types, only 20%–40% of patients benefit …

Recent developments have revolutionized the study of biomolecules. Among them are
molecular markers, amplification and sequencing of nucleic acids. The latter is classified into …

The aberrant expression of methylation and ncRNAs, two crucial regulators of epigenetic
modifications, has been widely demonstrated in cancer. The complex interplay between …

Simple Summary Chromatin and epigenetic alterations in cancer are responsible for a wide
range of transcriptional changes that link DNA mutations to tumor phenotype. In this review …

Simple Summary The medical care for patients with neuroendocrine tumors arising from the
intestines, pancreas, or stomach is frequently limited by the development resistance to …