Modeling neurodegenerative disorders in zebrafish

AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

Current state of modeling human psychiatric disorders using zebrafish

FV Costa, TO Kolesnikova, DS Galstyan… - International Journal of …, 2023 - mdpi.com
Psychiatric disorders are highly prevalent brain pathologies that represent an urgent, unmet
biomedical problem. Since reliable clinical diagnoses are essential for the treatment of …

Baicalein prevents stress-induced anxiety behaviors in zebrafish model

LK Selvaraj, S Jeyabalan, LS Wong, M Sekar… - Frontiers in …, 2022 - frontiersin.org
Baicalein is a flavonoid mainly obtained from plants with wide range of biological activities,
including neuroprotection. An acute and unexpected chronic stress (UCS) protocol has …

Beyond compliance: harmonising research and husbandry practices to improve experimental reproducibility using fish models

GC Paull, CJ Lee, CR Tyler - Biological Reviews, 2024 - Wiley Online Library
Reproducibility in animal research is impacted by the environment, by husbandry practices
in the laboratory and by the animals' provenance. These factors, however, are often not …

Developmental neurotoxicity and behavioral screening in larval zebrafish with a comparison to other published results

KA Jarema, DL Hunter, BN Hill, JK Olin, KN Britton… - Toxics, 2022 - mdpi.com
With the abundance of chemicals in the environment that could potentially cause
neurodevelopmental deficits, there is a need for rapid testing and chemical screening …

Cortisol dynamics and GR-dependent feedback regulation in zebrafish larvae exposed to repeated stress

LA Castillo-Ramírez, S Ryu, RJ De Marco - Biology Open, 2024 - journals.biologists.com
Zebrafish larvae show a rapid increase in cortisol in response to acute stressors, followed by
a decline. While these responses are documented, both the duration of the refractory period …

[HTML][HTML] Anaesthetic profile of thymol and menthol in zebrafish larvae model

RSF Vieira, D Sousa, LM Félix, CAS Venâncio - Aquaculture and Fisheries, 2024 - Elsevier
Aquaculture procedures such as capturing, handling, and transporting fish can lead to stress
in animals. For this reason, anaesthesia has been recommended to reduce fish stress …

[HTML][HTML] Chronic early life stress alters the neuroimmune profile and functioning of the developing zebrafish gut

CL Graves, E Norloff, D Thompson, O Kosyk… - Brain, Behavior, & …, 2023 - Elsevier
Chronic early life stress (ELS) potently impacts the developing central nervous and immune
systems and is associated with the onset of gastrointestinal disease in humans. Though the …

Elevated glucocorticoid alters the developmental dynamics of hypothalamic neurogenesis in zebrafish

H Eachus, MK Choi, A Tochwin, J Kaspareit… - Communications …, 2024 - nature.com
Exposure to excess glucocorticoid (GC) during early development is implicated in adult
dysfunctions. Reduced adult hippocampal neurogenesis is a well-known consequence of …

Leveraging big data to uncover the eco-evolutionary factors shaping behavioural development

SM Ehlman, U Scherer, D Bierbach… - … of the Royal …, 2023 - royalsocietypublishing.org
Mapping the eco-evolutionary factors shaping the development of animals' behavioural
phenotypes remains a great challenge. Recent advances in 'big behavioural data'research …