The Wistar Kyoto rat: a model of depression traits
EE Redei, ME Udell… - Current …, 2023 - benthamdirect.com
There is an ongoing debate about the value of animal research in psychiatry with valid lines
of reasoning stating the limits of individual animal models compared to human psychiatric …
of reasoning stating the limits of individual animal models compared to human psychiatric …
[HTML][HTML] Rosmarinic acid alleviate CORT-induced depressive-like behavior by promoting neurogenesis and regulating BDNF/TrkB/PI3K signaling axis
J Zeng, Z Xie, L Chen, X Peng, F Luan, J Hu… - Biomedicine & …, 2024 - Elsevier
Rosmarinic acid (RA), a natural phenolic acid compound with a variety of bioactive
properties. However, the antidepressant activity and mechanism of RA remain unclear. The …
properties. However, the antidepressant activity and mechanism of RA remain unclear. The …
Sleep deprivation alleviates depression-like behaviors in mice via inhibiting immune and inflammatory pathways and improving neuroplasticity
S Shi, M Zhang, W Xie, P Ju, N Chen, F Wang… - Journal of Affective …, 2023 - Elsevier
Background Sleep deprivation (SD) has been suggested to have a rapid antidepressant
effect. There is substantial evidence that neuroinflammation and neuroplasticity play critical …
effect. There is substantial evidence that neuroinflammation and neuroplasticity play critical …
Antidepressant-like effects of L-menthol mediated by alleviating neuroinflammation and upregulating the BDNF/TrkB signaling pathway in subchronically …
SM Zhu, R Xue, YF Chen, Y Zhang, J Du, FY Luo, H Ma… - Brain Research, 2023 - Elsevier
L-menthol (LM) is a safe and bioactive monoterpenoid from Mentha haplocalyxBriq., with
which an acute treatment has shown significant antidepressant-like effects potentially …
which an acute treatment has shown significant antidepressant-like effects potentially …
The impact of long-term isolation on anxiety, depressive-like and social behavior in aging Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) male rats
DI Mamedova, OA Nedogreeva, AO Manolova… - Scientific Reports, 2024 - nature.com
Aging is a complex process associated with multimorbidity. Hypertension, one of
widespread states, is among main causes of age-related alterations in behavior …
widespread states, is among main causes of age-related alterations in behavior …
Ameliorated Effects of Fucoidan on Dextran Sulfate Sodium-Induced Ulcerative Colitis and Accompanying Anxiety and Depressive Behaviors in Aged C57BL/6 Mice
S Li, Q Qian, Y Xie, Z Wu, H Yang, Y Yin… - Journal of Agricultural …, 2024 - ACS Publications
Fucoidan has shown better effects on the improvement of acute ulcerative colitis (UC).
However, the specific mechanisms by which fucoidan improves UC-related behavioral …
However, the specific mechanisms by which fucoidan improves UC-related behavioral …
Proteomic characterization of the medial prefrontal cortex in chronic restraint stress mice
Y Fu, Z Gu, H Cao, C Zuo, Y Huang, Y Song, J Miao… - Journal of …, 2024 - Elsevier
Depression is a prominent contributor to global disability. A growing body of data suggests
that depression is associated with the pathophysiology of the medial prefrontal cortex …
that depression is associated with the pathophysiology of the medial prefrontal cortex …
Ubiquitin ligase RFWD2 promotes dendritic spine and synapse formation by activating the ERK/PEA3/c-Jun pathway in rat cerebral cortical neurons
G Zhong, Z Fang, T Sun, M Ying, A Wang… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The regulation of protein degradation through the ubiquitin–proteasome system is essential
for normal brain development, axon growth, synaptic growth and plasticity. The E3 ubiquitin …
for normal brain development, axon growth, synaptic growth and plasticity. The E3 ubiquitin …
Evidence on differential role for alpha 1 and alpha 2 subtypes of AP-2 adaptin in the central nervous system
P Capella, J Asensio, M Troncoso, MA Sosa… - Neuroscience …, 2023 - Elsevier
Two subtypes of alpha (α) subunits, α1and α2, belonging to AP-2 complex have been
described in the central nervous system (CNS). The specific role of each subtype is still …
described in the central nervous system (CNS). The specific role of each subtype is still …
[图书][B] Ketamine's Effects on Adolescent Female Wistar-Kyoto and Wistar Rats
M Friar - 2023 - search.proquest.com
Abstract According to the National Institute of Mental Health (NIMH, 2021), the estimated
prevalence of major depressive disorder among adolescent females, is 25.2%. Currently …
prevalence of major depressive disorder among adolescent females, is 25.2%. Currently …