Regulation of bacterial virulence by Csr (Rsm) systems

CA Vakulskas, AH Potts, P Babitzke… - Microbiology and …, 2015 - Am Soc Microbiol
Most bacterial pathogens have the remarkable ability to flourish in the external environment
and in specialized host niches. This ability requires their metabolism, physiology, and …

Sticky situations: key components that control bacterial surface attachment

OE Petrova, K Sauer - Journal of bacteriology, 2012 - Am Soc Microbiol
The formation of bacterial biofilms is initiated by cells transitioning from the free-swimming
mode of growth to a surface. This review is aimed at highlighting the common themes that …

Post‐transcriptional regulation on a global scale: form and function of Csr/Rsm systems

T Romeo, CA Vakulskas… - Environmental …, 2013 - Wiley Online Library
Originally described as a repressor of gene expression in the stationary phase of growth,
CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation …

Diverse mechanisms and circuitry for global regulation by the RNA-binding protein CsrA

C Pourciau, YJ Lai, M Gorelik, P Babitzke… - Frontiers in …, 2020 - frontiersin.org
The carbon storage regulator (Csr) or repressor of stationary phase metabolites (Rsm)
system of Gammaproteobacteria is among the most complex and best-studied …

Improved bacterial single-cell RNA-seq through automated MATQ-seq and Cas9-based removal of rRNA reads

C Homberger, RJ Hayward, L Barquist, J Vogel - Mbio, 2023 - Am Soc Microbiol
Bulk RNA sequencing technologies have provided invaluable insights into host and
bacterial gene expression and associated regulatory networks. Nevertheless, the majority of …

Post-transcriptional global regulation by CsrA in bacteria

J Timmermans, L Van Melderen - Cellular and molecular life sciences, 2010 - Springer
Global regulation allows bacteria to rapidly modulate the expression of a large variety of
unrelated genes in response to environmental changes. Global regulators act at different …

Circuitry linking the Csr and stringent response global regulatory systems

AN Edwards, LM Patterson‐Fortin… - Molecular …, 2011 - Wiley Online Library
CsrA protein regulates important cellular processes by binding to target mRNAs and altering
their translation and/or stability. In Escherichia coli, CsrA binds to sRNAs, CsrB and CsrC …

Small Regulatory RNAs in the Control of Motility and Biofilm Formation in E. coli and Salmonella

F Mika, R Hengge - International journal of molecular sciences, 2013 - mdpi.com
Biofilm formation in Escherichia coli and other enteric bacteria involves the inverse
regulation of the synthesis of flagella and biofilm matrix components such as amyloid curli …

Bacterial sRNAs: regulation in stress

CH Hoe, CA Raabe, TS Rozhdestvensky… - International Journal of …, 2013 - Elsevier
Bacteria are often exposed to a hostile environment and have developed a plethora of
cellular processes in order to survive. A burgeoning list of small non-coding RNAs (sRNAs) …

Small RNAs and their role in biofilm formation

JR Chambers, K Sauer - Trends in microbiology, 2013 - cell.com
The formation of biofilms is initiated by bacteria transitioning from the planktonic to the
surface-associated mode of growth. Several regulatory systems have been described to …