Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …
Cu-catalyzed click reaction in carbohydrate chemistry
Cu (I)-catalyzed azide–alkyne 1, 3-dipolar cycloaddition (CuAAC), popularly known as the
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
“click reaction”, serves as the most potent and highly dependable tool for facile construction …
Recent progress on health effects and biosynthesis of two key sialylated human milk oligosaccharides, 3′-sialyllactose and 6′-sialyllactose
Y Zhu, J Zhang, W Zhang, W Mu - Biotechnology Advances, 2023 - Elsevier
Human milk oligosaccharides (HMOs), the third major solid component in breast milk, are
recognized as the first prebiotics for health benefits in infants. Sialylated HMOs are an …
recognized as the first prebiotics for health benefits in infants. Sialylated HMOs are an …
Recent progress in the development of indole-based compounds active against malaria, trypanosomiasis and leishmaniasis
PAF Pacheco, MMM Santos - Molecules, 2022 - mdpi.com
Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …
people in social and economic vulnerability. These diseases have attracted little investment …
Crystal structure of a novel two domain GH78 family α‐rhamnosidase from Klebsiella oxytoca with rhamnose bound
EC O'Neill, CEM Stevenson… - Proteins: Structure …, 2015 - Wiley Online Library
The crystal structure of the GH78 family α‐rhamnosidase from Klebsiella oxytoca (KoRha)
has been determined at 2.7 Å resolution with rhamnose bound in the active site of the …
has been determined at 2.7 Å resolution with rhamnose bound in the active site of the …
[HTML][HTML] Design, synthesis and the effect of 1, 2, 3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase
This work describes the synthesis of a series of sialylmimetic neoglycoconjugates
represented by 1, 4-disubstituted 1, 2, 3-triazole-sialic acid derivatives containing galactose …
represented by 1, 4-disubstituted 1, 2, 3-triazole-sialic acid derivatives containing galactose …
Enzyme catalysed production of sialylated human milk oligosaccharides and galactooligosaccharides by Trypanosoma cruzi trans-sialidase
Highlights•Optimised reaction conditions for Trypanosoma cruzi trans-sialidase.•Quantitative
production of 3′-sialyllactose from casein glycomacropeptide and lactose.•Enzymatic …
production of 3′-sialyllactose from casein glycomacropeptide and lactose.•Enzymatic …
Sialic acid: a sweet swing between mammalian host and Trypanosoma cruzi
L Freire-de-Lima, IA Oliveira, JL Neves… - Frontiers in …, 2012 - frontiersin.org
Commonly found at the outermost ends of complex carbohydrates in extracellular medium or
on outer cell membranes, sialic acids play important roles in a myriad of biological …
on outer cell membranes, sialic acids play important roles in a myriad of biological …
Biological Properties of 1H-1,2,3- and 2H-1,2,3-Triazoles
F de Carvalho da Silva, MFC Cardoso… - Chemistry of 1, 2, 3 …, 2015 - Springer
Triazoles, which are an important class of heterocyclic compounds, have been studied for
over a century and continue to attract considerable attention because of their broad range of …
over a century and continue to attract considerable attention because of their broad range of …
Glycoclusters presenting lactose on calix [4] arene cores display trypanocidal activity
A new series of water-soluble tetravalent glycoclusters incorporating β-lactosyl residues
attached to a central calix [4] arene core was synthesised using azide–alkyne Cu (I) …
attached to a central calix [4] arene core was synthesised using azide–alkyne Cu (I) …