Mechanisms of testicular torsion and potential protective agents

E Karaguzel, M Kadihasanoglu, O Kutlu - Nature Reviews Urology, 2014 - nature.com
Testicular torsion is a urological emergency most commonly seen in adolescence, involving
a decrease in blood flow in the testis resulting from torsion of the spermatic cord that can …

[HTML][HTML] Potential anti-inflammatory effect of erythropoietin in non-clinical studies in vivo: A systematic review

I Silva, C Alípio, R Pinto, V Mateus - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Erythropoietin (EPO) is a hypoxia-induced hormone produced in adult kidneys with
erythropoietic and non-erythropoietic effects. In vivo studies represent an important role to …

The potential protective and therapeutic effects of platelet-rich plasma on ischemia/reperfusion injury following experimental torsion/detorsion of testis in the Albino rat …

A Samy, M El-Adl, S Rezk, B Marghani, W Eldomany… - Life sciences, 2020 - Elsevier
Aims This study was designed to evaluate the protective and therapeutic efficacy of platelet-
rich plasma (PRP) against testicular degeneration and germ cell apoptosis after induced …

Protective effect of sildenafil citrate on contralateral testis injury after unilateral testicular torsion/detorsion

H Yíldíz, AS Durmus, H Şimşek, M Yaman - Clinics, 2011 - SciELO Brasil
OBJECTIVES: This study was designed to investigate prevention of contralateral testicular
injury with sildenafil citrate after unilateral testicular torsion/detorsion. METHODS: Thirty …

Testicular torsion in vivo models: Mechanisms and treatments

A Minas, S Mahmoudabadi, NS Gamchi… - …, 2023 - Wiley Online Library
Background Testicular torsion is a condition in which a testis rotates around its longitudinal
axis and twists the spermatic cord. This in turn results in a significant decrease in blood flow …

Erythropoietin and sildenafil protect against ischemia/reperfusion injury following testicular torsion in adult rats

ID Kostakis, N Zavras… - Experimental and …, 2017 - spandidos-publications.com
Testicular torsion/detorsion causes severe tissue damage due to ischemia/reperfusion
injury. The present study investigated the protective effect of erythropoietin and sildenafil …

Epigallocatechin-3-gallate inhibits apoptosis and protects testicular seminiferous tubules from ischemia/reperfusion-induced inflammation

M Al-Maghrebi, WM Renno, N Al-Ajmi - Biochemical and biophysical …, 2012 - Elsevier
Testicular torsion (TT) is a urologic emergency that may result in future infertility problems.
The pathologic process of TT is similar to an ischemia reperfusion injury (IRI). The purpose …

[HTML][HTML] Antioxidants in experimental ischemia-reperfusion injury of the testis: where are we heading towards?

G Vaos, N Zavras - World journal of methodology, 2017 - ncbi.nlm.nih.gov
Testicular torsion (TT) is a medical emergency that primary affects newborns and young
adolescents. It causes testicular injury due to the torsion of the spermatic cord and its …

Nigella sativa reduces tissue damage in rat ovaries subjected to torsion and detorsion: oxidative stress, proinflammatory response and histopathological evaluation

Y Bayir, Y Karagoz, E Karakus, A Albayrak… - Gynecologic and …, 2012 - karger.com
Background: To evaluate biochemically and histopathologically the effects of Nigella sativa
(NS) in experimental ischemia and ischemia/reperfusion (I/R) injury in rat ovaries. Methods …

Testicular torsion and spermatogenesis

OAH Alawamlh, R Flannigan, R Hayden… - Molecular Mechanisms …, 2021 - Springer
Testicular torsion (TT) is a common urologic emergency that can occur at any age. It is most
common in newborns and during puberty. Prompt evaluation and management is required …