Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Advancing the speed, sensitivity and accuracy of biomolecular detection using multi-length-scale engineering

SO Kelley, CA Mirkin, DR Walt, RF Ismagilov… - Nature …, 2014 - nature.com
Rapid progress in identifying disease biomarkers has increased the importance of creating
high-performance detection technologies. Over the last decade, the design of many …

Emerging role of nanomaterials in circulating tumor cell isolation and analysis

HJ Yoon, M Kozminsky, S Nagrath - ACS nano, 2014 - ACS Publications
Circulating tumor cells (CTCs) are low frequency cells found in the bloodstream after having
been shed from a primary tumor. These cells are research targets because of the information …

Near-infrared light-responsive hydrogel for specific recognition and photothermal site-release of circulating tumor cells

SW Lv, Y Liu, M Xie, J Wang, XW Yan, Z Li, WG Dong… - ACS …, 2016 - ACS Publications
Isolation of single circulating tumor cells (CTCs) from patients is a very challenging
technique that may promote the process of individualized antitumor therapies. However …

[HTML][HTML] Circulating tumor cells: moving biological insights into detection

L Chen, AM Bode, Z Dong - Theranostics, 2017 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) have shown promising potential as liquid biopsies that
facilitate early detection, prognosis, therapeutic target selection and monitoring treatment …

Beyond the capture of circulating tumor cells: next‐generation devices and materials

BJ Green, T Saberi Safaei, A Mepham… - Angewandte Chemie …, 2016 - Wiley Online Library
Over the last decade, significant progress has been made towards the development of
approaches that enable the capture of rare circulating tumor cells (CTCs) from the blood of …

Nanoparticle‐mediated binning and profiling of heterogeneous circulating tumor cell subpopulations

RM Mohamadi, JD Besant, A Mepham… - Angewandte Chemie …, 2015 - Wiley Online Library
The analysis of circulating tumor cells (CTCs) is an important capability that may lead to new
approaches for cancer management. CTC capture devices developed to date isolate a bulk …

Multifunctional" smart" particles engineered from live immunocytes: toward capture and release of cancer cells.

C Huang, G Yang, Q Ha, J Meng… - … Materials (Deerfield Beach …, 2014 - europepmc.org
Multifunctional" smart" particles with magnetic, topographic, cell-targeting, and stimulus-
responsive properties are obtained using a" live template" strategy. These particles exhibit …

Label-free detection and enumeration of rare circulating tumor cells by bright-field image cytometry and multi-frame image correlation analysis

Z Du, Y Li, B Chen, L Wang, Y Hu, X Wang, W Zhang… - Lab on a Chip, 2022 - pubs.rsc.org
Identification and enumeration of circulating tumor cells (CTCs) in peripheral blood are
proved to correlate with the progress of metastatic cancer and can provide valuable …

High-purity capture of CTCs based on micro-beads enhanced isolation by size of epithelial tumor cells (ISET) method

N Sun, X Li, Z Wang, Y Li, R Pei - Biosensors and Bioelectronics, 2018 - Elsevier
In this paper, we develop a low-cost size-based microfluidic chip using conventional
polycarbonate membrane to isolate CTCs from blood, and propose a strategy to increase …