Dupuytren disease (DD) is a fibroproliferative disorder of unknown etiology that often results
in shortening and thickening of the palmar fascia, leading to permanent and irreversible …

Objective: Excisional surgery is the mainstay of treatment of Dupuytren's disease. Although
outcomes are generally good, complications are common. The objective of this study was to …

PURPOSE: To evaluate long-term efficacy and safety of collagenase clostridium histolyticum
(CCH) after the third year of a 5-year nontreatment follow-up study, Collagenase Option for …

Musculoskeletal fibromatoses represent a wide spectrum of fibroblastic and myofibroblastic
neoplasms with similar pathologic appearances and variable clinical behavior. These …

Background This large population-based study was conducted to estimate the prevalence of
Dupuytren's disease in US adults and describe associated treatment patterns. Methods A …

The treatment of progressive Dupuytren contractures has historically been and continues to
be largely surgical. Although a number of surgical interventions do exist, limited palmar …

The Tenth Edition of Hunter's Diseases of Occupations has been fully revised and updated,
presenting all practitioners considering an occupational cause for a patient's condition with …

PURPOSE: The JOINT I (United States) and JOINT II (Australia and Europe) studies
evaluated the efficacy and safety of collagenase clostridium histolyticum (CCH) injection for …

Introduction Peyronie disease (PD) is a progressive fibrotic disorder of the penile tunica
albuginea that results in fibrotic penile plaques and can lead to penile deformity …

Safety was evaluated for collagenase Clostridium histolyticum (CCH) based on 11 clinical
trials (N= 1082) and compared with fasciectomy data in a structured literature review of 48 …