Functional polarization of tumor-associated macrophages dictated by metabolic reprogramming

W Zeng, F Li, S Jin, PC Ho, PS Liu, X Xie - Journal of Experimental & …, 2023 - Springer
Macrophages are highly plastic in different tissues and can differentiate into functional
subpopulations under different stimuli. Tumor-associated macrophages (TAMs) are one of …

Mechanisms of macrophage polarization in insulin signaling and sensitivity

L Orliaguet, E Dalmas, K Drareni, N Venteclef… - Frontiers in …, 2020 - frontiersin.org
Type-2 diabetes (T2D) is a disease of two etiologies: metabolic and inflammatory. At the
cross-section of these etiologies lays the phenomenon of metabolic inflammation. Whilst …

Elevated TyG index predicts progression of coronary artery calcification

K Park, CW Ahn, SB Lee, S Kang, JS Nam… - Diabetes …, 2019 - Am Diabetes Assoc
OBJECTIVE To investigate the triglyceride-glucose (TyG) index association with coronary
artery calcification (CAC) progression in adult Koreans. RESEARCH DESIGN AND …

The impact of the stress hyperglycemia ratio on short-term and long-term poor prognosis in patients with acute coronary syndrome: insight from a large cohort study in …

J Yang, Y Zheng, C Li, J Gao, X Meng, K Zhang… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE In recent years, some studies have indicated that a novel marker described as
the stress hyperglycemia ratio (SHR) can reflect true acute hyperglycemic status and is …

A lysosome-targeted DNA nanodevice selectively targets macrophages to attenuate tumours

C Cui, K Chakraborty, XA Tang, KQ Schoenfelt… - Nature …, 2021 - nature.com
Activating CD8+ T cells by antigen cross-presentation is remarkably effective at eliminating
tumours. Although this function is traditionally attributed to dendritic cells, tumour-associated …

Triglyceride glucose index for predicting cardiovascular outcomes after percutaneous coronary intervention in patients with type 2 diabetes mellitus and acute …

X Ma, L Dong, Q Shao, Y Cheng, S Lv, Y Sun… - Cardiovascular …, 2020 - Springer
Abstract Background The triglyceride glucose (TyG) index, a simple surrogate estimate of
insulin resistance, has been demonstrated to predict cardiovascular (CV) disease morbidity …

Triglyceride glucose index is an independent predictor for the progression of coronary artery calcification in the absence of heavy coronary artery calcification at …

KB Won, EJ Park, D Han, JH Lee, SY Choi… - Cardiovascular …, 2020 - Springer
Background Data on the relationship between the triglyceride glucose (TyG) index and
coronary artery calcification (CAC) progression is limited. This longitudinal study evaluated …

Triglyceride-glucose index and common carotid artery intima-media thickness in patients with ischemic stroke

M Miao, G Zhou, A Bao, Y Sun, H Du, L Song… - Cardiovascular …, 2022 - Springer
Abstract Background Triglyceride glucose (TyG) index was recently reported to be
associated with an increased risk of the development and recurrence of cardiovascular …

Foam cells: one size doesn't fit all

V Guerrini, ML Gennaro - Trends in immunology, 2019 - cell.com
Chronic inflammation in many infectious and metabolic diseases, and some cancers, is
accompanied by the presence of foam cells. These cells form when the intracellular lipid …

Liver macrophages and inflammation in physiology and physiopathology of non‐alcoholic fatty liver disease

R Thibaut, MC Gage, I Pineda‐Torra… - The FEBS …, 2022 - Wiley Online Library
Non‐alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, being a common comorbidity of type 2 diabetes and with important links to …