Sequences of directly adjacent stereogenic centers were first discovered for the
monosaccharides, which therefore constituted the first focus of interest in Stereoselective …

A series of new 6, 7-disubstituted-4-(arylamino) quinoline-3-carbonitrile derivatives that
function as irreversible inhibitors of human epidermal growth factor receptor-2 (HER-2) and …

Corynantheine-type alkaloids are major components of the Mitragyna speciosa, also known
as kratom, that exhibit unique pharmacological activity. However, no universal method to …

Hikizimycin (anthelmycin) is a nucleoside antibiotic and anthelmintic agent that represents
the most structurally complex member of the long-chain carbohydrate class of …

A continuous flow system for the multiparameter (flow rate, temperature, residence time,
stoichiometry) optimization of the DIBALH reduction of esters to aldehydes is described …

We investigate a group B• that includes Artin's braid group B∞ and Thompson's group F.
The elements of B• are represented by braids diagrams in which the distances between the …

We report a concise, enantioselective synthesis of the yohimbine alkaloids (−)-rauwolscine
and (−)-alloyohimbane. The key transformation involves a highly enantio-and …

A convenient method for the conversion of lactones to lactols is described. The
hydrosilylation to lactols is carried out via air-stable titanocene difluoride or a titanocene …

A Lewis base promoted deprotonative pronucleophile addition to silyl acetals has been
developed and applied to the iridium-catalyzed reductive Horner–Wadsworth–Emmons …

The conditions for the regiospecific singlet oxygen oxidation of various 2, 4-disubstituted
furans 9 to 4-substituted-2 (5H)-furanones 3 are developed. The presence of a C-2 …