Chronic liver diseases such as nonalcoholic fatty liver disease (NAFLD) or viral hepatitis are
characterized by persistent inflammation and subsequent liver fibrosis. Liver fibrosis critically …

Changes in the intestinal microbiome have been associated with obesity and type 2
diabetes, in epidemiological studies and studies of the effects of fecal transfer in germ-free …

Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …

The liver is a dynamic organ that plays critical roles in many physiological processes,
including the regulation of systemic glucose and lipid metabolism. Dysfunctional hepatic …

Obesity is a global epidemic characterized by energy disequilibrium, metabolic disorder, fat
mass development, and chronic low-grade inflammation, which significantly affects the …

The global obesity epidemic has necessitated the search for better intervention strategies
including the exploitation of the health benefits of some gut microbiota and their metabolic …

Diverse evidence suggests that the gut microbiota is involved in the development of obesity
and associated comorbidities. It has been reported that the composition of the gut microbiota …

Hepatic steatosis is an underlying feature of nonalcoholic fatty liver disease (NAFLD), which
is the most common form of liver disease and is present in up to∼ 70% of individuals who …

We are facing a global metabolic health crisis provoked by an obesity epidemic. Here we
report the human gut microbial composition in a population sample of 123 non-obese and …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …