Cannabis and synaptic reprogramming of the developing brain

A Bara, JMN Ferland, G Rompala, H Szutorisz… - Nature Reviews …, 2021 - nature.com
Recent years have been transformational in regard to the perception of the health risks and
benefits of cannabis with increased acceptance of use. This has unintended …

[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation

JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Associations between prenatal cannabis exposure and childhood outcomes: results from the ABCD study

SE Paul, AS Hatoum, JD Fine, EC Johnson… - JAMA …, 2021 - jamanetwork.com
Importance In light of increasing cannabis use among pregnant women, the US Surgeon
General recently issued an advisory against the use of marijuana during pregnancy …

The essential medicinal chemistry of cannabidiol (CBD)

KM Nelson, J Bisson, G Singh, JG Graham… - Journal of medicinal …, 2020 - ACS Publications
This Perspective of the published essential medicinal chemistry of cannabidiol (CBD)
provides evidence that the popularization of CBD-fortified or CBD-labeled health products …

The preconception environment and sperm epigenetics

C Marcho, OA Oluwayiose, JR Pilsner - Andrology, 2020 - Wiley Online Library
Background Infertility is a common reproductive disorder, with male factor infertility
accounting for approximately half of all cases. Taking a paternal perceptive, recent research …

Epigenetic changes in sperm are associated with paternal and child quantitative autistic traits in an autism-enriched cohort

JI Feinberg, R Schrott, C Ladd-Acosta… - Molecular …, 2024 - nature.com
There is a need to consider paternal contributions to autism spectrum disorder (ASD) more
strongly. Autism etiology is complex, and heritability is not explained by genetics alone …

[HTML][HTML] Geotemporospatial and causal inference epidemiological analysis of US survey and overview of cannabis, cannabidiol and cannabinoid genotoxicity in …

AS Reece, GK Hulse - BMC pediatrics, 2022 - Springer
Background Cannabinoids including cannabidiol have recognized genotoxic activities but
their significance has not been studied broadly epidemiologically across the teratological …

Refraining from use diminishes cannabis-associated epigenetic changes in human sperm

R Schrott, SK Murphy, JL Modliszewski… - Environmental …, 2021 - academic.oup.com
Cannabis use alters sperm DNA methylation, but the potential reversibility of these changes
is unknown. Semen samples from cannabis users and non-user controls were collected at …

[HTML][HTML] Epidemiological overview of multidimensional chromosomal and genome toxicity of cannabis exposure in congenital anomalies and cancer development

AS Reece, GK Hulse - Scientific reports, 2021 - nature.com
Cannabis and cannabinoids are implicated in multiple genotoxic, epigenotoxic and
chromosomal-toxic mechanisms and interact with several morphogenic pathways, likely …

Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes

JO Lo, JC Hedges, G Girardi - American journal of obstetrics and …, 2022 - Elsevier
Cannabis is the most commonly used federally illegal drug in the United States and the
world, especially among people of reproductive age. In addition, the potency of cannabis …