WNTs and their downstream effectors regulate proliferation, death, and migration and cell
fate decision. Deregulation of WNT signaling is associated with various cancers including …

Glioblastoma multiforme (GBM) is the most aggressive form of brain cancer due to its highly
invasive nature that impedes the surgical removal of all tumor cells, making relapse …

Cell migration and invasion are highly regulated processes involved in both physiological
and pathological conditions. Here we show that autophagy modulation regulates the …

Tumor dissemination and metastatic behavior account for the vast majority of cancer
associated mortality. Epithelial tumors achieve this progressive state via epithelial-to …

Here we show that activation of the canonical WNT/β-catenin pathway increases the
expression of stem cell genes and promotes the migratory and invasive capacity of …

The epithelial‐to mesenchymal (EMT) process is increasingly recognized for playing a key
role in the progression, dissemination, and therapy resistance of epithelial tumors …

Epithelial-to-mesenchymal transition (EMT) and its reverse process MET naturally occur
during development and in tissue repair in vertebrates. EMT is also recognized as the …

Background Ionizing irradiation is an effective treatment for malignant glioma (MG);
however, a higher rate of recurrence with more aggressive phenotypes is a vital issue …

Background: Epithelial-mesenchymal transition (EMT) is regulated by induction factors,
transcription factor families and an array of signaling pathways genes, and has been …

Bacterial meningitis is a serious infection of the CNS that results when blood-borne bacteria
are able to cross the blood-brain barrier (BBB). Group B Streptococcus (GBS) is the leading …