The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …

Therapy resistance is a major problem when treating cancer patients as cancer cells
develop mechanisms that counteract the effect of therapeutic compounds, leading to fit and …

Cancer stem cells, a relatively small group of self-renewing cancer cells, were first isolated
from acute myeloid leukemia. These cells can play a crucial role in tumor metastasis …

Cancers are heterogeneous at the cell level, and the mechanisms leading to cancer
heterogeneity could be clonal evolution or cancer stem cells. Cancer stem cells are resistant …

Platinum compounds (cisplatin and carboplatin) represent the most active anticancer agents
in clinical use both of lung cancer in mono-and combination therapies. However, platinum …

Simple Summary The world of small molecules in solid tumors as cancer stem cells (CSCs),
circulating tumor cells (CTCs) and cancer-associated fibroblasts (CAFs) continues to be …

Cancer stem cells (CSCs) have been considered the key drivers of cancer initiation and
progression due to their unlimited self-renewal capacity and their ability to induce tumor …

Purpose Cancer stem cells (CSC) are the most common causes of lung cancer relapse and
mouse resistance to chemotherapy. CD166 was identified as CSC marker for lung cancer …

Cancer stem cells (CSCs) are the subpopulation of cells present within a tumor with the
properties of self-renewing, differentiating, and proliferating. Owing to the presence of ATP …

Nowadays, the focus of researchers is on perceiving the heterogeneity observed in a tumor.
The researchers studied the role of a specific subset of cancer cells with high resistance to …