Neurodegenerative and mental disorders are a public health burden with pharmacological
treatments of limited efficacy. Organoselenium compounds are receiving great attention in …

The objective of the present review was to provide a timely update on the molecular
mechanisms underlying the beneficial role of Se in Alzheimer's disease pathogenesis, and …

Systemic administration of 3-nitropropionic acid (3-NPA) is commonly used to induce
Huntington's disease (HD)-like symptoms in experimental animals. Here, the potential …

Alzheimer's disease (AD) is of multifactorial origin, and still presents several gaps regarding
its development and progression. Disorders of the cholinergic system are well known to be …

The prominence of autophagy in the modulation of neurodegenerative disorders has
sparked interest to investigate its stimulation in Alzheimer's disease (AD). Nobiletin …

Melatonin is a hormone secreted by the pineal gland, it can be associated with circadian
rhythms, aging and neuroprotection. Melatonin levels are decreased in sporadic Alzheimer's …

Alzheimer's disease (AD) is an age-related, multifactorial progressive neurodegenerative
disorder manifested by cognitive impairment and neuronal death in the brain areas like …

With the increasingly serious aging of the global population, dementia has already become
a severe clinical challenge on a global scale. Dementia caused by Alzheimer's disease (AD) …

Alzheimer's disease is identified by pathological hallmarks such as intracellular
neurofibrillary tangles (NFTs) and extracellular amyloid β plaques. Several hypotheses exist …

The understanding that zidovudine (ZDV or azidothymidine, AZT) inhibits the RNA-
dependent RNA polymerase (RdRp) of SARS-CoV-2 and that chalcogen atoms can …