Principles and challenges of genome-wide DNA methylation analysis
PW Laird - Nature Reviews Genetics, 2010 - nature.com
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many
eukaryotes that has important implications for normal biology and disease. Therefore …
eukaryotes that has important implications for normal biology and disease. Therefore …
[HTML][HTML] Biomedical text mining and its applications in cancer research
F Zhu, P Patumcharoenpol, C Zhang, Y Yang… - Journal of biomedical …, 2013 - Elsevier
Cancer is a malignant disease that has caused millions of human deaths. Its study has a
long history of well over 100years. There have been an enormous number of publications on …
long history of well over 100years. There have been an enormous number of publications on …
Lnc2Cancer: a manually curated database of experimentally supported lncRNAs associated with various human cancers
Abstract Lnc2Cancer (http://www. bio-bigdata. net/lnc2cancer) is a manually curated
database of cancer-associated long non-coding RNAs (lncRNAs) with experimental support …
database of cancer-associated long non-coding RNAs (lncRNAs) with experimental support …
EWAS Open Platform: integrated data, knowledge and toolkit for epigenome-wide association study
Abstract Epigenome-Wide Association Study (EWAS) has become a standard strategy to
discover DNA methylation variation of different phenotypes. Since 2018, we have developed …
discover DNA methylation variation of different phenotypes. Since 2018, we have developed …
Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer
AE Teschendorff, U Menon, A Gentry-Maharaj… - Genome …, 2010 - genome.cshlp.org
Polycomb group proteins (PCGs) are involved in repression of genes that are required for
stem cell differentiation. Recently, it was shown that promoters of PCG target genes (PCGTs) …
stem cell differentiation. Recently, it was shown that promoters of PCG target genes (PCGTs) …
MethHC: a database of DNA methylation and gene expression in human cancer
Abstract We present MethHC (http://MethHC. mbc. nctu. edu. tw), a database comprising a
systematic integration of a large collection of DNA methylation data and mRNA/microRNA …
systematic integration of a large collection of DNA methylation data and mRNA/microRNA …
[PDF][PDF] Overview of BioNLP'09 shared task on event extraction
The paper presents the design and implementation of the BioNLP'09 Shared Task, and
reports the final results with analysis. The shared task consists of three sub-tasks, each of …
reports the final results with analysis. The shared task consists of three sub-tasks, each of …
Challenges in biomarker discovery: combining expert insights with statistical analysis of complex omics data
JE McDermott, J Wang, H Mitchell… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: The advent of high throughput technologies capable of comprehensive
analysis of genes, transcripts, proteins and other significant biological molecules has …
analysis of genes, transcripts, proteins and other significant biological molecules has …
Telomerase reactivation following telomere dysfunction yields murine prostate tumors with bone metastases
Z Ding, CJ Wu, M Jaskelioff, E Ivanova, M Kost-Alimova… - Cell, 2012 - cell.com
To determine the role of telomere dysfunction and telomerase reactivation in generating pro-
oncogenic genomic events and in carcinoma progression, an inducible telomerase reverse …
oncogenic genomic events and in carcinoma progression, an inducible telomerase reverse …
DiseaseMeth version 2.0: a major expansion and update of the human disease methylation database
The human disease methylation database (DiseaseMeth, http://bioinfo. hrbmu. edu.
cn/diseasemeth/) is an interactive database that aims to present the most complete …
cn/diseasemeth/) is an interactive database that aims to present the most complete …