[HTML][HTML] Multifunctional magnetic iron oxide nanoparticles: an advanced platform for cancer theranostics

S Zhao, X Yu, Y Qian, W Chen, J Shen - Theranostics, 2020 - ncbi.nlm.nih.gov
Multifunctional magnetic nanoparticles and derivative nanocomposites have aroused great
concern for multimode imaging and cancer synergistic therapies in recent years. Among the …

[HTML][HTML] Polymer-hybrid nanoparticles: Current advances in biomedical applications

DCF Soares, SC Domingues, DB Viana… - Biomedicine & …, 2020 - Elsevier
The unique properties of polymer-hybrid nanosystems enable them to play an important role
in different fields such as biomedical applications. Hybrid materials, which are formed by …

ROS‐responsive polyprodrug nanoparticles for triggered drug delivery and effective cancer therapy

X Xu, PE Saw, W Tao, Y Li, X Ji, S Bhasin… - Advanced …, 2017 - Wiley Online Library
The application of nanoparticles (NPs) to drug delivery has led to the development of novel
nanotherapeutics for the treatment of various diseases including cancer. However, clinical …

Manganese-Based Nanoactivator Optimizes Cancer Immunotherapy via Enhancing Innate Immunity

L Hou, C Tian, Y Yan, L Zhang, H Zhang, Z Zhang - ACS nano, 2020 - ACS Publications
Cyclic GMP-AMP synthase (cGAS) and stimulator of interferon genes (STING) are essential
components of the innate immune sensors to cytosolic DNA and elicit type I interferon (IFN) …

[HTML][HTML] Polymer bioconjugates: Modern design concepts toward precision hybrid materials

C Chen, DYW Ng, T Weil - Progress in Polymer Science, 2020 - Elsevier
The conjugation of synthetic polymers with various biomolecules provides an easy access to
biohybrid materials which combine advantages from both the synthetic world and Nature …

Utilization of polymer-lipid hybrid nanoparticles for targeted anti-cancer therapy

A Mohanty, S Uthaman, IK Park - Molecules, 2020 - mdpi.com
Cancer represents one of the most dangerous diseases, with 1.8 million deaths worldwide.
Despite remarkable advances in conventional therapies, these treatments are not effective …

Factors Relating to the Biodistribution & Clearance of Nanoparticles & Their Effects on In Vivo Application

Y Wei, L Quan, C Zhou, Q Zhan - Nanomedicine, 2018 - Taylor & Francis
Nanoparticles have promising biomedical applications for drug delivery, tumor imaging and
tumor treatment. Pharmacokinetics are important for the in vivo application of nanoparticles …

Lipid-polymer hybrid nanocarriers for delivering cancer therapeutics

T Date, V Nimbalkar, J Kamat, A Mittal… - Journal of controlled …, 2018 - Elsevier
Cancer remained a major cause of death providing diversified challenges in terms of
treatment including non-specific toxicity, chemoresistance and relapse. Nanotechnology …

Fucoidan-doxorubicin nanoparticles targeting P-selectin for effective breast cancer therapy

M Jafari, V Sriram, Z Xu, GM Harris, JY Lee - Carbohydrate polymers, 2020 - Elsevier
Fucoidan, a type of sulfated polysaccharide known for its anticoagulant, anti-tumor and anti-
inflammatory effects, has been reported to have strong affinity towards P-selectin. P-selectin …

Microfluidics for producing poly (lactic-co-glycolic acid)-based pharmaceutical nanoparticles

X Li, X Jiang - Advanced drug delivery reviews, 2018 - Elsevier
Microfluidic chips allow the rapid production of a library of nanoparticles (NPs) with distinct
properties by changing the precursors and the flow rates, significantly decreasing the time …