Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing …

JC Berentschot, HA Drexhage… - Frontiers in …, 2023 - frontiersin.org
Background Many patients with SARS-CoV-2 infection develop long COVID with fatigue as
one of the most disabling symptoms. We performed clinical and immune profiling of fatigued …

Abdominal surgery induces long-lasting changes in expression and binding of CTCF with impact on Major Histocompatibility Complex II transcription in circulating …

BH Siegler, JN Thon, M Altvater, J Schenz, J Larmann… - Plos one, 2023 - journals.plos.org
Background Postoperative immunosuppression has been recognized as an important driver
of surgery-related morbidity and mortality. It is characterized by lymphocyte depression and …

Monocytes perturbation implicated in the association of stress hyperglycemia with postoperative poor prognosis in non-diabetic patients with Stanford type-A acute …

S Zhao, D Fu, W Luo, WY Shen, XM Miao, JY Li… - Cardiovascular …, 2024 - Springer
Objectives The study aimed to investigate the interaction of intraoperative stress
hyperglycemia with monocyte functions and their impact on major adverse events (MAEs) in …

Early dynamic changes to monocytes following major surgery are associated with subsequent infections

TAC Snow, AV Waller, R Loye, F Ryckaert… - Frontiers in …, 2024 - frontiersin.org
Background Post-operative infections are a common cause of morbidity following major
surgery. Little is understood about how major surgery perturbs immune function leading to …

Postoperative lymphopaenia as a risk factor for postoperative infections in cancer surgery: A prospective multicentre cohort study (the EVALYMPH study)

L Petit, B Pastene, G Dupont, B Baffeleuf… - European Journal of …, 2024 - journals.lww.com
BACKGROUND Stress due to surgical trauma decreases postoperative lymphocyte counts
(LCs), potentially favouring the occurrence of postoperative infections (PIs). OBJECTIVES …

The Controlling Nutritional Status (CONUT) Score for Prediction of Microvascular Flap Complications in Reconstructive Surgery

RP Rocans, J Zarins, E Bine, R Deksnis… - Journal of clinical …, 2023 - mdpi.com
Microvascular flap surgery is a widely acknowledged procedure for significant defect
reconstruction. Multiple flap complication risk factors have been identified, yet there are …

Postoperative Innate Immune Dysregulation, Proteomic, and Monocyte Epigenomic Changes After Colorectal Surgery: A Substudy of a Randomized Controlled Trial

KI Albers-Warlé, LS Helder, LA Groh, F Polat… - Anesthesia & …, 2022 - journals.lww.com
BACKGROUND: Colorectal surgery is associated with moderate-to-severe postoperative
complications in over 25% of patients, predominantly infections. Monocyte epigenetic …