This review summarizes the main achievements in basic and clinical research of
atherosclerosis. Focusing on desialylation as the first and the most important reaction of …

Catalytic antibodies made it feasible to develop new catalysts, which had previously been
the subject of research. Scientists have discovered natural antibodies that can hydrolyze …

Abs, antibodies; Abzs, abzymes or catalytically active antibodies; SLE, systemic lupus
erythematosus; HT, Hashimoto's thyroiditis; MS, Multiple sclerosis; ODN …

The pathologic role of autoantibodies in autoimmune disease is widely accepted. Recently,
we reported that anti-myelin basic protein (MBP) serum Abs from multiple sclerosis (MS) …

DNA-hydrolyzing activity of IgG autoantibodies from sera of patients with various types of
lymphoproliferative diseases was investigated. The association of DNA-hydrolyzing activity …

The protein 3D8 single-chain variable fragment (3D8 scFv) has potential anti-viral activity
due to its ability to penetrate into cells and hydrolyze nucleic acids. Probiotic Lactobacillus …

Background: New natural amylolytic abzymes (Abs) for catalytically active antibodies from
human milk have been identified and investigated. Methods: The amylolytic activity of …

Most of the data accumulated through studies on natural catalytic autoantibodies indicate
that production scales up markedly in pathological abnormalities. We have previously …

This review summarizes literature data on natural abzymes. Peculiar features of their
functioning and substrate specificity are considered in comparison with traditional enzymes …

Proteolytic activity of polyclonal IgG antibodies (Abs) from the blood of AIDS patients was
analyzed for the first time. These Abs were shown to display higher activity in hydrolysis of β …