An ongoing journey of chalcone analogues as single and multi-target ligands in the field of Alzheimer's disease: A review with structural aspects

P Sharma, M Singh - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is a chronic and irreversible neurodegenerative disorder with
progressive dementia and cognitive impairment. AD poses severe health challenge in …

A quinquennial review on recent advancements and developments in search of anti-malarial agents

TM Dhameliya, D Kathuria, TM Patel… - Current Topics in …, 2023 - benthamdirect.com
Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

Halogenated coumarin–chalcones as multifunctional monoamine oxidase-B and butyrylcholinesterase inhibitors

NA Rehuman, JM Oh, LR Nath, A Khames… - ACS …, 2021 - ACS Publications
A series of halogenated coumarin–chalcones were synthesized, characterized, and their
inhibitory activities against monoamine oxidases (MAOs), acetylcholinesterase (AChE) …

Design, synthesis, and anticancer activity studies of novel quinoline-chalcone derivatives

YF Guan, XJ Liu, XY Yuan, WB Liu, YR Li, GX Yu… - Molecules, 2021 - mdpi.com
The chalcone and quinoline scaffolds are frequently utilized to design novel anticancer
agents. As the continuation of our work on effective anticancer agents, we assumed that …

Synthesis and Photophysical, Electrochemical, and DFT Studies of Piperidyl and Pyrrolidinyl Chalcones

H Baig, A Iqbal, A Rasool, SZ Hussain, J Iqbal… - ACS …, 2023 - ACS Publications
Small organic molecules with interesting optical and electrochemical properties find
applications as organic luminescent materials. In this work, we report the synthesis of novel …

Chalcones against the hallmarks of cancer: A mini-review

PS de Souza, GCC Bibá, EDN Melo… - Natural Product …, 2021 - Taylor & Francis
Abstract Chalcones (1, 3-diphenylpropen-1-ones) are a class of flavonoids that have been
shown a broad spectrum of biological activities with therapeutic potential. Naturally …

[HTML][HTML] Synthesis, photophysical, voltammetric, and DFT studies of 4-aminochalones

H Baig, R Irfan, A Rasool, SZ Hussain… - … of Photochemistry and …, 2023 - Elsevier
Aminochalcones, with a DAD architecture, were synthesized using Claisen-Schmidt
condensation. The compounds were characterized by FTIR, melting point, HRMS, 1 H, and …

Coordination chemistry of chalcones and derivatives and their use as corrosion inhibitors: A comprehensive review

AK Singh, VC Anadebe, M Singh, N Arshad… - Coordination Chemistry …, 2024 - Elsevier
Chalcones, α, β-unsaturated ketones, being the by-products of the condensation reactions
between acetophenones and aromatic aldehydes widely found their applications in …

New Chalcone Derivatives Containing 2, 4-Dichlorobenzenesulfonamide Moiety with Anticancer and Antioxidant Properties

A Bułakowska, J Sławiński, A Hering, M Gucwa… - International Journal of …, 2023 - mdpi.com
Chalcones and their derivatives, both natural and synthetic, exhibit diverse biological
activities. In this study, we focused on designing and synthesizing (E)-2, 4-dichloro-N-(4 …

Synthesis, structural and biological properties of the ring-A sulfonamido substituted chalcones: A review

MJ Mphahlele - Molecules, 2021 - mdpi.com
Sulfonamidochalcones continue to assert themselves as versatile synthetic intermedi-ates
and several articles continue to appear in literature describing their synthesis, chemical …