Active resolution of acute inflammation is a previously unrecognized interface between
innate and adaptive immunity. Once thought to be a passive process, the resolution of …

Resolution of inflammation and the return of tissues to homeostasis are essential. Efforts to
identify molecular events governing termination of self-limited inflammation uncovered …

Acute inflammation in the lung is essential to health. So too is its resolution. In response to
invading microbes, noxious stimuli, or tissue injury, an acute inflammatory response is …

Originally regarded as just membrane constituents and energy storing molecules, lipids are
now recognised as potent signalling molecules that regulate a multitude of cellular …

The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …

Lipoxins (LXs) or the lipoxygenase interaction products are generated from arachidonic acid
via sequential actions of lipoxygenases and subsequent reactions to give specific …

Before we discuss lipids and their role in homeostasis and host defense, we will recount the
essence of the inflammatory response. Inflammation is a reaction of the microcirculation; it's …

Chronic inflammation is a component of numerous diseases including autoimmune,
metabolic, neurodegenerative, and cancer. The discovery and characterization of …

The family of resolvins consists of omega-3 fatty acid-derived mediators, including E series
resolvins generated from eicosapentaenoic acid (EPA), and carry potent anti-inflammatory …

The release and oxygenation of arachidonic acid is held to be a critical event in regulating
key processes in host defense, inflammation and hemodynamics [P--4]. oxygenation of …