Constructions and properties of physically cross-linked hydrogels based on natural polymers
The diverse structures and unique properties of hydrogels have attracted significant
attentions in recent years. Compared to chemically cross-linked hydrogels, natural polymer …
attentions in recent years. Compared to chemically cross-linked hydrogels, natural polymer …
Thermosensitive chitosan/glycerophosphate-based hydrogel and its derivatives in pharmaceutical and biomedical applications
S Supper, N Anton, N Seidel… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Thermogelling chitosan (CS)/glycerophosphate (GP) solutions have been
reported as a new type of parenteral in situ forming depot system. These free-flowing …
reported as a new type of parenteral in situ forming depot system. These free-flowing …
Achieving long-acting local analgesia using an intelligent hydrogel encapsulated with drug and pH regulator
W Guo, D Cao, W Rao, T Sun, Y Wei… - … Applied Materials & …, 2023 - ACS Publications
Local anesthetics are important for the treatment of postoperative pain. Since a single
injection of the solution of a drug such as bupivacaine (BUP) works only for a few hours, it is …
injection of the solution of a drug such as bupivacaine (BUP) works only for a few hours, it is …
Photothermally triggered biomimetic drug delivery of Teriparatide via reduced graphene oxide loaded chitosan hydrogel for osteoporotic bone regeneration
X Wang, W Guo, L Li, F Yu, J Li, L Liu, B Fang… - Chemical Engineering …, 2021 - Elsevier
Stimuli-responsive biomaterials have attracted more attention in drug delivery area as
controlled release with physiologically relevant temporal and spatial context. Teriparatide is …
controlled release with physiologically relevant temporal and spatial context. Teriparatide is …
Transplantation of allogenic chondrocytes with chitosan hydrogel-demineralized bone matrix hybrid scaffold to repair rabbit cartilage injury
Z Man, X Hu, Z Liu, H Huang, Q Meng, X Zhang, L Dai… - Biomaterials, 2016 - Elsevier
Cartilage tissue engineering is the hotspot of cartilage repair. The allogenic chondrocytes
appear to be a promising source of seed cells in cartilage tissue engineering. In this study …
appear to be a promising source of seed cells in cartilage tissue engineering. In this study …
Polymeric nanogels as versatile nanoplatforms for biomedical applications
Nanomaterials have found extensive biomedical applications in the past few years because
of their small size, low molecular weight, larger surface area, enhanced biological, and …
of their small size, low molecular weight, larger surface area, enhanced biological, and …
Poloxamer 407/188 binary thermosensitive hydrogels as delivery systems for infiltrative local anesthesia: Physico-chemical characterization and pharmacological …
ACS Akkari, JZB Papini, GK Garcia… - Materials Science and …, 2016 - Elsevier
In this study, we reported the development and the physico-chemical characterization of
poloxamer 407 (PL407) and poloxamer 188 (PL188) binary systems as hydrogels for …
poloxamer 407 (PL407) and poloxamer 188 (PL188) binary systems as hydrogels for …
Micro-and nanofabrication of chitosan structures for regenerative engineering
Repair and regeneration of human tissues and organs using biomaterials, cells and/or
growth factors is the ultimate goal of tissue engineers. One of the grand challenges in this …
growth factors is the ultimate goal of tissue engineers. One of the grand challenges in this …
Synthesis of nanocapsules blended polymeric hydrogel loaded with bupivacaine drug delivery system for local anesthetics and pain management
W Deng, Y Yan, P Zhuang, X Liu, K Tian, W Huang… - Drug …, 2022 - Taylor & Francis
Local anesthetics are used clinically for the control of postoperative pain management. This
study aimed to develop chitosan (CS) with genipin (GP) hydrogels as the hydrophilic lipid …
study aimed to develop chitosan (CS) with genipin (GP) hydrogels as the hydrophilic lipid …
Long-acting hydrogel/microsphere composite sequentially releases dexmedetomidine and bupivacaine for prolonged synergistic analgesia
W Zhang, W Xu, C Ning, M Li, G Zhao, W Jiang, J Ding… - Biomaterials, 2018 - Elsevier
Local anesthetics are a class of drugs, which have wide applications in the treatment of
acute and chronic pain. However, their analgesic effects only last for a few hours because of …
acute and chronic pain. However, their analgesic effects only last for a few hours because of …