[HTML][HTML] Epidemiology of peritoneal dialysis outcomes

AK Bello, IG Okpechi, MA Osman, Y Cho… - Nature Reviews …, 2022 - nature.com
Peritoneal dialysis (PD) is an important home-based treatment for kidney failure and
accounts for 11% of all dialysis and 9% of all kidney replacement therapy globally. Although …

[HTML][HTML] Endothelial dysfunction in chronic kidney disease, from biology to clinical outcomes: a 2020 update

S Roumeliotis, F Mallamaci, C Zoccali - Journal of Clinical Medicine, 2020 - mdpi.com
The vascular endothelium is a dynamic, functionally complex organ, modulating multiple
biological processes, including vascular tone and permeability, inflammatory responses …

Diagnosis, evaluation, prevention, and treatment of chronic kidney disease–mineral and bone disorder: Synopsis of the kidney disease: improving global outcomes …

M Ketteler, GA Block, P Evenepoel… - Annals of internal …, 2018 - acpjournals.org
Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical
Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of …

[HTML][HTML] Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

PP Centeno, A Herberger, HC Mun, C Tu… - Nature …, 2019 - nature.com
Extracellular phosphate regulates its own renal excretion by eliciting concentration-
dependent secretion of parathyroid hormone (PTH). However, the phosphate-sensing …

Chronic kidney disease—mineral and bone disorders: pathogenesis and management

JB Cannata-Andía, B Martín-Carro… - Calcified tissue …, 2021 - Springer
The key players of the chronic kidney disease-mineral and bone disorders (CKD-MBD) are
calcium, phosphate, PTH, FGF23, and the vitamin D hormonal system. The progressive …

Factors affecting outcomes in patients reaching end-stage kidney disease worldwide: differences in access to renal replacement therapy, modality use, and …

BM Robinson, T Akizawa, KJ Jager, PG Kerr, R Saran… - The Lancet, 2016 - thelancet.com
More than 2 million people worldwide are being treated for end-stage kidney disease
(ESKD). This Series paper provides an overview of incidence, modality use (in-centre …

FGF23 and klotho at the intersection of kidney and cardiovascular disease

D Edmonston, A Grabner, M Wolf - Nature Reviews Cardiology, 2024 - nature.com
Cardiovascular disease is the leading cause of death in patients with chronic kidney disease
(CKD). As CKD progresses, CKD-specific risk factors, such as disordered mineral …

Arterial calcification in chronic kidney disease: key roles for calcium and phosphate

CM Shanahan, MH Crouthamel, A Kapustin… - Circulation …, 2011 - Am Heart Assoc
Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney
disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …

The heart and vascular system in dialysis

C Wanner, K Amann, T Shoji - The Lancet, 2016 - thelancet.com
The heart and the vascular tree undergo major structural and functional changes when
kidney function declines and renal replacement therapy is required. The many …

Recent changes in therapeutic approaches and association with outcomes among patients with secondary hyperparathyroidism on chronic hemodialysis: the DOPPS …

F Tentori, M Wang, BA Bieber… - Clinical Journal of the …, 2015 - journals.lww.com
Results Median parathyroid hormone increased from phase 1 to phase 4 in all regions
except for Japan, where it remained stable. Prescriptions of intravenous vitamin D analogs …