The vascular endothelium is a dynamic, functionally complex organ, modulating multiple biological processes, including vascular tone and permeability, inflammatory responses …
M Ketteler, GA Block, P Evenepoel… - Annals of internal …, 2018 - acpjournals.org
Description: The Kidney Disease: Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of …
PP Centeno, A Herberger, HC Mun, C Tu… - Nature …, 2019 - nature.com
Extracellular phosphate regulates its own renal excretion by eliciting concentration- dependent secretion of parathyroid hormone (PTH). However, the phosphate-sensing …
The key players of the chronic kidney disease-mineral and bone disorders (CKD-MBD) are calcium, phosphate, PTH, FGF23, and the vitamin D hormonal system. The progressive …
More than 2 million people worldwide are being treated for end-stage kidney disease (ESKD). This Series paper provides an overview of incidence, modality use (in-centre …
Cardiovascular disease is the leading cause of death in patients with chronic kidney disease (CKD). As CKD progresses, CKD-specific risk factors, such as disordered mineral …
Vascular calcification contributes to the high risk of cardiovascular mortality in chronic kidney disease (CKD) patients. Dysregulation of calcium (Ca) and phosphate (P) metabolism is …
C Wanner, K Amann, T Shoji - The Lancet, 2016 - thelancet.com
The heart and the vascular tree undergo major structural and functional changes when kidney function declines and renal replacement therapy is required. The many …
F Tentori, M Wang, BA Bieber… - Clinical Journal of the …, 2015 - journals.lww.com
Results Median parathyroid hormone increased from phase 1 to phase 4 in all regions except for Japan, where it remained stable. Prescriptions of intravenous vitamin D analogs …