N-Terminal Proline Editing for the Synthesis of Peptides with Mercaptoproline and Selenoproline: Mechanistic Insights Lead to Greater Efficiency in Proline Native …

BA Ludwig, CR Forbes, NJ Zondlo - ACS Chemical Biology, 2024 - ACS Publications
Native chemical ligation (NCL) at proline has been limited by cost and synthetic access. In
addition, prior examples of NCL using mercaptoproline have exhibited stalling of the …