The guardians of pulmonary harmony: alveolar macrophages orchestrating the symphony of lung inflammation and tissue homeostasis

L Pervizaj-Oruqaj, MR Ferrero, U Matt… - European Respiratory …, 2024 - Eur Respiratory Soc
Recent breakthroughs in single-cell sequencing, advancements in cellular and tissue
imaging techniques, innovations in cell lineage tracing, and insights into the epigenome …

Toward systemic lipofuscin removal

M Renteln - Rejuvenation Research, 2024 - liebertpub.com
Lipofuscin is indigestible garbage that accumulates in the autophagic vesicles and cytosol of
postmitotic cells with age. Drs. Brunk and Terman postulated that lipofuscin accumulation is …

Tissue-resident immune cells: from defining characteristics to roles in diseases

J Li, C Xiao, C Li, J He - Signal Transduction and Targeted Therapy, 2025 - nature.com
Tissue-resident immune cells (TRICs) are a highly heterogeneous and plastic subpopulation
of immune cells that reside in lymphoid or peripheral tissues without recirculation. These …

Clearing the way for new therapies in clonal hematopoiesis

VY Ling, SW Lane - Blood Advances, 2023 - ashpublications.org
In this issue of Blood Advances, Gustafsson et al examined the effect of an anti-CD45
antibody drug conjugate (ADC) on tissue-resident myeloid cells (TRM) in healthy and …