Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Imaging has played a variety of roles in the study of Alzheimer disease (AD) over the past
four decades. Initially, computed tomography (CT) and then magnetic resonance imaging …

Structural imaging based on magnetic resonance is an integral part of the clinical
assessment of patients with suspected Alzheimer dementia. Prospective data on the natural …

The structure of the brain is constantly changing from birth throughout the lifetime, meaning
that normal aging, free from dementia, is associated with structural brain changes. This …

Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) measures abilities broadly
related to executive function (EF), including WAIS-R Digit Symbol Substitution, Digit Span …

Until the mid 1990s, available evidence regarding neurocognitive aging could be
summarized in a simple statement: cognitive deficits in healthy older adults are largest for …

There are many reports of relations between age and cognitive variables and of relations
between age and variables representing different aspects of brain structure and a few …

Both normal aging and Alzheimer's disease (AD) are associated with changes in cognition,
grey and white matter volume, white matter integrity, neural activation, functional …

Objective: Delirium duration is predictive of long-term cognitive impairment in intensive care
unit survivors. Hypothesizing that a neuroanatomical basis may exist for the relationship …

Investigation of relationships between age-related changes in regional brain volumes and
changes in domain-specific cognition could provide insights into the neural underpinnings of …