In this review, we consider the evidence that a reduction in neurogenesis underlies aging-
related cognitive deficits and impairments in disorders such as Alzheimer's disease (AD) …

This review summarizes and organizes the literature concerning the effects of microglia on
neurogenesis, particularly focusing on the subgranular zone (SGZ) of the hippocampus and …

Aging causes changes in the hippocampus that may lead to cognitive decline in older
adults. In young animals, exercise increases hippocampal neurogenesis and improves …

Increasing evidence suggests that regular exercise improves brain health and promotes
synaptic plasticity and hippocampal neurogenesis. Exercise improves learning, but specific …

Rats treated with low dose irradiation, to inhibit adult hippocampal neurogenesis, and
control rats were administered a nonmatching‐to‐sample (NMTS) task, which measured …

The hippocampus is an area of the brain that undergoes dramatic plasticity in response to
experience and hormone exposure. The hippocampus retains the ability to produce new …

Maintenance of neurogenesis in adult hippocampus is important for functions such as mood
and memory. As exposure to unpredictable chronic stress (UCS) results in decreased …

Past research suggested that androgens may play a role in the regulation of adult
neurogenesis within the dentate gyrus. We tested this hypothesis by manipulating androgen …

We tested whether daily exercise modulates immune and neuroimmune cytokines,
hippocampus-dependent behavior and hippocampal neurogenesis in aging male F344 rats …

Executive functions supported by prefrontal cortical (PFC) systems provide essential control
and planning mechanisms to guide goal-directed behavior. As such, age-related alterations …