As one of the earth's key ecosystems, rivers have been intensively studied and modelled
through the application of machine learning (ML). With the amount of large data available …

Abstract Reaching the Sustainable Development Goal (SDG) 6 on water and sanitation is
fundamentally important and conditional to the achievement of all the other SDGs …

Background Immune checkpoint blockade (ICB) has been approved for the treatment of
triple-negative breast cancer (TNBC), since it significantly improved the progression-free …

Itraconazole is an orally active antifungal agent that has complex and highly variable
absorption kinetics that is highly affected by food. This study aimed to develop a population …

This tutorial presents the application of an R package, RxODE, that facilitates quick, efficient
simulations of ordinary differential equation models completely within R. Its application is …

Rivers act as a natural source of greenhouse gases (GHGs). However, anthropogenic
activities can largely alter the chemical composition and microbial communities of rivers …

The potential of using ChatGPT in pharmacometrics was explored in this study, with a focus
on developing a population pharmacokinetic (PK) model for standard half‐life factor VIII. Our …

Abstract Since 2013, STRait Razor has enabled analysis of massively parallel sequencing
(MPS) data from various marker systems such as short tandem repeats, single nucleotide …

Drug discovery and development (DDD) is a highly complex process that necessitates
precise monitoring and extensive data analysis at each stage. Furthermore, the DDD …

An on‐farm research network is an organization of farmers that conducts agronomic
experiments under local conditions. It is common that an elementary statistical analysis be …