Cancer is nowadays one of the most devastating diseases, being a central public health
problem as well as a leading cause of death worldwide. In an attempt to fight this illness …

Phthalides, mainly isolated from two genera: Ligusticum and Angelica of the Apiceae (syn
Umbelliferae) family, are thought to be a potent natural compound with many therapeutic …

Resorcinolic lipids are described as potential examples of selective chemotherapeutic
adjuvants that can enhance the effects of cyclophosphamide (CYC) while promoting cell …

Polyketides with the isochroman-3-one pharmacophore are rare among fungal natural
products as their biosynthesis requires an unorthodox S-type aromatic ring cyclization …

Alternanthera littoralis P. Beauv is a plant native to Brazil that exhibits various beneficial
activities including antioxidant, antibacterial, antifungal, antiprotozoal, anti-hyperalgesic, and …

The global spread of multidrug-resistant strains has prompted the scientific community to
explore novel sources of chemicals with antimicrobial activity. The aim of the study was to …

Cardanol is an effective antioxidant and is a compound with antimutagenic and antitumoral
activity. Here, we evaluated the genotoxic and mutagenic potential of saturated side chain …

Pilosocereus gounellei (Cactaceae) is used to treat wounds and inflammation. In this study,
we evaluated whether the saline extract from its stem would have genotoxic or anti …

Inflammation is a natural response of the organism to an infection, trauma, or cellular stress.
Pain is the first symptom of acute and chronic inflammation. The standard class of …

Aims Previous studies performed by our research group indicated that cytosporone
analogues are capable of prevent or repair DNA damages. This work presents the …