Cajal was probably the first neurobiologist to suggest that plasticity of nerve cells almost
completely disappeared during aging. However, we know today that neural plasticity is still …

Stress can be defined as a brain–body reaction towards stimuli arising from the environment
or from internal cues that are interpreted as a disruption of homeostasis. The organization of …

The effects of aging on glutamate neurotransmission in the brain is reviewed and evaluated.
Glutamate is the neurotransmitter in most of the excitatory synapses and appears to be …

Using microdialysis, we investigated the circadian rhythms of the extracellular
concentrations of dopamine, glutamate and γ‐aminobutyric acid (GABA) in the striatum and …

Cannabinoids and ethanol can activate the same reward pathways, which could suggest
endocannabinoid involvement in the rewarding effects of ethanol. The high ethanol …

The aim of the present study was to investigate the effects of environmental enrichment on
the neurogenesis and the extracellular concentrations of glutamate and GABA in the …

Previous experimental studies have shown that the prefrontal cortex (PFC) regulates the
activity of the nucleus accumbens (NAc), and in particular the release of dopamine in this …

Previous studies have demonstrated opposing roles for adenosine A1 and A2A receptors in
the modulation of extracellular levels of glutamate and dopamine in the striatum. In the …

Brain microdialysis has become a frequently used method to study the extracellular
concentrations of neurotransmitters in specific areas of the brain. For years, and this is still …

Aging is characterized by the decline in many of the individual's capabilities. It has been
recognized that the brain undergoes structural and functional changes during aging that are …