Protein-based adjuvants for vaccines as immunomodulators of the innate and adaptive immune response: Current knowledge, challenges, and future opportunities

DA Díaz-Dinamarca, ML Salazar, BN Castillo… - Pharmaceutics, 2022 - mdpi.com
New-generation vaccines, formulated with subunits or nucleic acids, are less immunogenic
than classical vaccines formulated with live-attenuated or inactivated pathogens. This …

Mollusc N-glycosylation: structures, functions and perspectives

E Staudacher - Biomolecules, 2021 - mdpi.com
Molluscs display a sophisticated N-glycan pattern on their proteins, which is, in terms of
involved structural features, even more diverse than that of vertebrates. This review …

[HTML][HTML] MiRNA-mRNA integration analysis of three continuous embryonic stages of Chinese horseshoe crab Tachypleus tridentatus

Y Huang, Y Qiao, S Zhong, X Zhang, M Hu, K Kwan… - Aquaculture …, 2024 - Elsevier
Horseshoe crabs are marine chelicerates which have existed for about 450 million years.
Their long coexistence with microbial pathogens presumably is due to their efficient immune …

Immunotherapeutic Potential of Mollusk Hemocyanins in Murine Model of Melanoma

E Stoyanova, N Mihaylova, N Ralchev, S Bradyanova… - Marine Drugs, 2024 - mdpi.com
The development of antitumor drugs and therapy requires new approaches and molecules,
and products of natural origin provide intriguing alternatives for antitumor research …

Regulatory role of ETS1 transcription factor in hemocytes proliferation in Anadara granosa

J Wang, M Wang, X Chen, Y Xu, H Jin, S Zha, Y Bao… - Aquaculture, 2025 - Elsevier
The ETS1 transcription factor is crucial in the process of biological development. In
vertebrate, ETS1 plays a pivotal role in promoting endothelial cell proliferation and …

Structural insights into a functional unit from an immunogenic mollusk hemocyanin

SM Muñoz, G Vallejos-Baccelliere, A Manubens… - Structure, 2024 - cell.com
Mollusk hemocyanins, among the largest known proteins, are used as immunostimulants in
biomedical and clinical applications. The hemocyanin of the Chilean gastropod …

[HTML][HTML] Primer registro de concentración de zinc y cobre en Sphyrna tiburo: bioindicador de la salud de la costa de Campeche, México

T Esparza-May, ME Bergés-Tiznado… - Revista internacional …, 2023 - scielo.org.mx
Se evaluó la concentración de zinc (Zn) y cobre (Cu) en 43 muestras de hígado y 77 de
músculos del tiburón cabeza de pala (Sphyrna tiburo), como indicador del estado de salud …

Shrimp hemocyanin elicits a potent humoral response in mammals and is favorable to hapten conjugation

H Sun, M Wei, A Guo, C Zhang, Y Wang, R Huang… - Scientific Reports, 2024 - nature.com
Conjugation to a carrier protein is essential to give rise to the antigenicity of hapten. Three
carrier proteins eg KLH (Keyhole Limpet hemocyanin), BSA (bovine serum albumin), and …

First record of copper and zinc concentrations in Sphyrna tiburo: bioindicator of Campeche, Mexico, coast health

T Esparza-May, ME Bergés-Tiznado… - Revista internacional …, 2023 - scielo.org.mx
ESPARZA-MAY, Teresa et al. First record of copper and zinc concentrations in Sphyrna
tiburo: bioindicator of Campeche, Mexico, coast health. Rev. Int. Contam. Ambient [online] …

The Oxygen Transporters

MH Rosove - Life's Blood: The Story of Hemoglobin, 2024 - Springer
Oxygen transporters are ubiquitous in nature. They have one principal purpose, to deliver
oxygen where it is needed for energy production. They are highly complex proteins with an …