A review: PI3K/AKT/mTOR signaling pathway and its regulated eukaryotic translation initiation factors may be a potential therapeutic target in esophageal squamous …

R Huang, Q Dai, R Yang, Y Duan, Q Zhao… - Frontiers in …, 2022 - frontiersin.org
Esophageal squamous cell carcinoma (ESCC) is a malignant tumor developing from the
esophageal squamous epithelium, and is the most common histological subtype of …

High-dose versus conventional-dose irradiation in cisplatin-based definitive concurrent chemoradiotherapy for esophageal cancer: a systematic review and pooled …

T Song, X Liang, M Fang, S Wu - Expert review of anticancer …, 2015 - Taylor & Francis
We investigate whether high-dose (HD,≥ 60 Gy) radiotherapy in definitive concurrent
chemoradiotherapy (CCRT) based on cisplatin could yield benefits compared to …

Esophageal cancer practice guidelines 2022 edited by the Japan esophageal society: part 1

Y Kitagawa, R Ishihara, H Ishikawa, Y Ito, T Oyama… - Esophagus, 2023 - Springer
The primary objective of these guidelines was to provide general clinicians with information
that would guide them to make informed choices from the available diagnosis/treatment …

Salvage surgery for esophageal cancer: how to improve outcomes?

C Cohen, W Tessier, C Gronnier, F Renaud… - Annals of surgical …, 2018 - Springer
Background Locoregional recurrence rates after definitive chemoradiotherapy (dCRT) for
locally advanced esophageal cancer (EC) are high. Salvage surgery (SALV) is considered …

A meta-analysis on salvage surgery as a potentially curative procedure in patients with isolated local recurrent or persistent esophageal cancer after …

Z Faiz, WPM Dijksterhuis, JGM Burgerhof… - European Journal of …, 2019 - Elsevier
Background Isolated local recurrent or persistent esophageal cancer (EC) after curative
intended definitive (dCRT) or neoadjuvant chemoradiotherapy (nCRT) with initially omitted …

Neoadjuvant chemoradiotherapy followed by esophagectomy with three-field lymph node dissection for thoracic esophageal squamous cell carcinoma patients with …

Y Sato, S Motoyama, Y Wada, A Wakita, Y Kawakita… - Cancers, 2021 - mdpi.com
Simple Summary This study aimed to clarify the efficacy of neoadjuvant chemoradiotherapy
(NACRT) followed by esophagectomy with three-field lymph node (LN) dissection for clinical …

SP4 facilitates esophageal squamous cell carcinoma progression by activating PHF14 transcription and Wnt/β-Catenin signaling

L Wei, C Deng, B Zhang, G Wang, Y Meng… - Molecular Cancer …, 2024 - AACR
Specificity protein 4 transcription factor (SP4), a member of the Sp/Krüppel-like family (KLF),
could bind to GT and GC box promoters, and plays an essential role in transcriptional …

Salvage esophagectomy for initially unresectable locally advanced T4 esophageal squamous cell carcinoma

A Okamura, M Hayami, R Kozuki, K Takahashi… - Esophagus, 2020 - Springer
Background Definitive chemoradiotherapy (dCRT) for esophageal squamous cell carcinoma
(ESCC) is a potentially curative treatment modality, even for patients with unresectable T4 …

Association of preoperative nutritional status with prognosis in patients with esophageal cancer undergoing salvage esophagectomy

M Sakai, M Sohda, T Miyazaki, T Yoshida… - Anticancer …, 2018 - ar.iiarjournals.org
Background: To investigate whether malnutrition is associated with poor prognosis of
patients who undergo salvage esophagectomy. We examined the association between the …

Selective lymphadenectomy for salvage esophagectomy in patients with esophageal squamous cell carcinoma

S Mayanagi, R Haneda, M Inoue, K Ishii… - Annals of Surgical …, 2022 - Springer
Background Extensive lymph node dissection increases the risk of postoperative
complications, especially in salvage surgery, after definitive chemoradiotherapy (≥ 50 Gy) …