Context: Ever since the discovery of cyclodextrins, a family of cyclic oligosaccharides based
on α (1→ 4) linkage among glucopyranose subunits, these versatile supramolecular hosts …

For decades, naturally produced plants have been studied and used in herbalism (herbal
medicines). Despite being natural, these products were not of any interest of any of the …

For more than one hundred years, several treatments against malaria have been proposed
but they have systematically failed, mainly due to the occurrence of drug resistance in part …

Artemisinin (Art) is a natural sesquiterpene lactone that is claimed to exhibit various
bioactivities. The poor solubility of Art in both water and oil hinders its application in …

A microemulsion system based on ionic liquid (IL) and deep eutectic compound was
proposed to improve the transdermal delivery of artemisinin. Deep eutectic lidocaine …

Nasal administration has been proposed as a potential approach for the delivery of drugs to
the central nervous system. Ribavirin (RBV), an antiviral drug potentially useful to treat viral …

Structural mass spectrometry (MS) techniques are fast and sensitive analytical methods to
identify noncovalent guest/host complexation phenomena for desirable solution-phase …

Artemether (ARM) is a poorly water soluble and poorly permeable drug effective against
acute and severe falciparum malaria, hence there is a strong need to improve its solubility …

Background: Bioavailability, one of the prime pharmacokinetic properties of a drug, is
defined as the fraction of an administered dose of unchanged drug that reaches the systemic …

Background. Artesunate is one of the most potent, rapidly acting and therapeutically
versatile antimalarial drugs. Its efficacy is hampered by poor aqueous solubility and stability …