The LC8 family members of dynein light chains (DYNLL1 and DYNLL2 in vertebrates) are
highly conserved ubiquitous eukaryotic homodimer proteins that interact, besides dynein …

Almost all animals contain mitochondria of maternal origin only, but the exact mechanisms
underlying this phenomenon are still vague. We investigated the fate of Drosophila paternal …

Subcellular location and activation of Tank Binding Kinase 1 (TBK1) govern precise
progression through mitosis. Either loss of activated TBK1 or its sequestration from the …

During Drosophila melanogaster oogenesis, the proper localization of gurken (grk) mRNA
and protein is required for the establishment of the dorsal–ventral axis of the egg and future …

The attachment of the cytoskeleton to the plasma membrane is crucial in controlling the
polarized transport of cell-fate-determining molecules. Attachment involves adaptor …

During Drosophila oogenesis, the targeted localization of gurken (grk) mRNA leads to the
establishment of the axis polarity of the egg. In early stages of oogenesis, grk mRNA is found …

The Drosophila egg chamber provides a useful model for examining mechanisms by which
cell fates are specified and maintained in the context of a complex tissue. The egg chamber …

The morphogenesis of Drosophila sensory bristles is dependent on the function of their actin
and microtubule cytoskeleton. Actin filaments are important for bristle shape and elongation …

While previous studies have shown that microtubules (MTs) are essential for maintaining the
highly biased axial growth of the Drosophila bristle, the mechanism for this process has …

Cell polarization requires asymmetric localization of numerous mRNAs, proteins and
organelles. The movement of cargo towards the minus end of microtubules mostly depends …