[HTML][HTML] Engineering the next generation of cell-based therapeutics

CJ Bashor, IB Hilton, H Bandukwala… - Nature Reviews Drug …, 2022 - nature.com
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …

Electroactive biomaterials and systems for cell fate determination and tissue regeneration: design and applications

Z Liu, X Wan, ZL Wang, L Li - Advanced Materials, 2021 - Wiley Online Library
During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

[HTML][HTML] Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

[HTML][HTML] Bacterial biopolymers: from pathogenesis to advanced materials

MF Moradali, BHA Rehm - Nature Reviews Microbiology, 2020 - nature.com
Bacteria are prime cell factories that can efficiently convert carbon and nitrogen sources into
a large diversity of intracellular and extracellular biopolymers, such as polysaccharides …

Anti‐friction MSCs delivery system improves the therapy for severe osteoarthritis

X Yan, B Yang, Y Chen, Y Song, J Ye, Y Pan… - Advanced …, 2021 - Wiley Online Library
Osteoarthritis (OA) is a musculoskeletal disorder disease affecting about 500 million people
worldwide and mesenchymal sem cells (MSCs) therapy has been demonstrated as a …

Light‐triggered in situ gelation to enable robust photodynamic‐immunotherapy by repeated stimulations

Z Meng, X Zhou, J Xu, X Han, Z Dong… - Advanced …, 2019 - Wiley Online Library
Photodynamic therapy (PDT) has shown the potential of triggering systemic antitumor
immune responses. However, while the oxygen‐deficient hypoxic tumor microenvironment …

[HTML][HTML] Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands

Y Wang, ER Zoneff, JW Thomas, N Hong… - Nature …, 2023 - nature.com
Injectable biomimetic hydrogels have great potential for use in regenerative medicine as
cellular delivery vectors. However, they can suffer from issues relating to hypoxia, including …

[HTML][HTML] Porous nanocellulose gels and foams: Breakthrough status in the development of scaffolds for tissue engineering

FV Ferreira, CG Otoni, J Kevin, HS Barud, LMF Lona… - Materials Today, 2020 - Elsevier
We report on the latest scientific advances related to the use of porous foams and gels
prepared with cellulose nanofibrils (CNF) and nanocrystals (CNC) as well as bacterial …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

Materials roles for promoting angiogenesis in tissue regeneration

JH Lee, P Parthiban, GZ Jin, JC Knowles… - Progress in Materials …, 2021 - Elsevier
Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …