A systematic review of the effect of delayed appropriate antibiotic treatment on the outcomes of patients with severe bacterial infections

EJ Zasowski, M Bassetti, F Blasi, H Goossens, J Rello… - Chest, 2020 - Elsevier
Background Patients with severe bacterial infections often experience delay in receiving
appropriate treatment. Consolidated evidence of the impact of delayed appropriate …

Management of adults with hospital-acquired and ventilator-associated pneumonia: 2016 clinical practice guidelines by the Infectious Diseases Society of America …

AC Kalil, ML Metersky, M Klompas… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Effects of inappropriate administration of empirical antibiotics on mortality in adults with bacteraemia: systematic review and meta-analysis

YP Hung, CC Lee, WC Ko - Frontiers in medicine, 2022 - frontiersin.org
Introduction Bloodstream infections are associated with high mortality rates and contribute
substantially to healthcare costs, but a consensus on the prognostic benefits of appropriate …

High prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates: A 5-year retrospective study at a Tertiary …

A Siriphap, T Kitti, A Khuekankaew… - Frontiers in Cellular …, 2022 - frontiersin.org
Background The global emergence and spread of extended-spectrum beta-lactamase
(ESBL)-producing Enterobacterales, especially Escherichia coli and Klebsiella pneumoniae …

Risk Factors and Mortality of Elderly Patients with Hospital-Acquired Pneumonia of Carbapenem-Resistant Klebsiella pneumoniae Infection

C Zhou, L Sun, H Li, L Huang, X Liu - Infection and Drug …, 2023 - Taylor & Francis
Purpose Hospital-acquired pneumonia (HAP) caused by carbapenem-resistant K.
pneumoniae (CRKP), especially in elderly patients, results in high morbidity and mortality …

High mortality from blood stream infection in Addis Ababa, Ethiopia, is due to antimicrobial resistance

T Seboxa, W Amogne, W Abebe, T Tsegaye, A Azazh… - PloS one, 2015 - journals.plos.org
Background Managing blood stream infection in Africa is hampered by lack of
bacteriological support needed for antimicrobial stewardship, and background data needed …

Epidemiology and Outcomes of Community-Acquired Escherichia coli Pneumonia

TM John, A Deshpande, K Brizendine… - Open Forum …, 2022 - academic.oup.com
Background E. coli is an under-recognized cause of bacterial community-acquired
pneumonia (CAP). The objective of this study was to describe the epidemiology, risk factors …

Klebsiella pneumoniae harboring carbapenemase genes in Taiwan: its evolution over 20 years, 1998–2019

CC Lai, WL Yu - International Journal of Antimicrobial Agents, 2021 - Elsevier
Klebsiella pneumoniae (K. pneumoniae) is an important pathogen causing various types of
human infections in Taiwan. Carbapenemases have increasingly been reported in …

[HTML][HTML] Carbapenem-sparing beta-lactam/beta-lactamase inhibitors versus carbapenems for bloodstream infections caused by extended-spectrum beta-lactamase …

H Zhang, J Xu, Q Xiao, Y Wang, J Wang, M Zhu… - International Journal of …, 2023 - Elsevier
Abstract Objectives Bloodstream infections (BSIs) caused by extended-spectrum beta-
lactamase-producing Enterobacteriaceae (ESBL-PE) have become a worldwide public …

Comparison between carbapenems and β-lactam/β-lactamase inhibitors in the treatment for bloodstream infections caused by extended-spectrum β-lactamase …

M Muhammed, ME Flokas, M Detsis… - Open forum …, 2017 - academic.oup.com
Background Carbapenems are widely used for the management of bloodstream infections
(BSIs) caused by extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL …