Synthesis of chirally purified substituted benzothiazole diamines

P Raje, RR Gadikota, JX Chen, OV Lapina… - US Patent …, 2013 - Google Patents
Methods for preparing chirally purified substituted 4, 5, 6, 7-tetrahydro-benzothiazole
diamines such as, for example,(6R) 2-amino-4, 5, 6, 7-tetrahydro-6-(propylamino) benzothia …

Compositions and methods of using r (+) pramipexole

M Bozik, G Hebrank, T Petzinger - US Patent App. 11/733,642, 2007 - Google Patents
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Modified release formulations of (6R)-4, 5, 6, 7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine and methods of using the same

ME Bozik, T Petzinger, V Gribkoff - US Patent 8,524,695, 2013 - Google Patents
Modified release pharmaceutical compositions (controlled release, sustained release,
and/or extended release) of the R-(+) enantiomer of pramipexole (RPPX) and methods of …

Compositions and methods of using (R)-pramipexole

ME Bozik, T Petzinger, V Gribkoff - US Patent 8,518,926, 2013 - Google Patents
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Compositions and methods for treating chronic urticaria

ME Bozik, S Dworetzky - US Patent 9,763,918, 2017 - Google Patents
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Compositions of R (+) and S (−) pramipexole and methods of using the same

ME Bozik, T Petzinger, V Gribkoff - US Patent 8,017,598, 2011 - Google Patents
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Compositions and Methods of Using (R)-Pramipexole

ME Bozik, V Gribkoff - US Patent App. 13/059,713, 2011 - Google Patents
Pharmaceutical compositions of (R)-pramipexole and one or more secondary therapeutic
agents such as, for example dopamine agonists, dopaminergic agonists, COMT inhibitors …

Compositions and methods for treating conditions related to elevated levels of eosinophils and/or basophils

ME Bozik, G Hebrank, T Petzinger… - US Patent …, 2020 - Google Patents
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Compositions and methods for treating conditions related to increased eosinophils

ME Bozik, G Hebrank, W Farwell, T Petzinger… - US Patent …, 2016 - Google Patents
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eosinophils - Google Patents US9468630B2 - Compositions and methods for treating conditions …

Synthesis of amine substituted 4, 5, 6, 7-tetrahydrobenzothiazole compounds

W Chen, M Humora, DA Kwok, WF Kiesman… - US Patent …, 2016 - Google Patents
The present invention is related to an improved process for the preparation of amino-
substituted 4, 5, 6, 7-tetrahydrobenzothiazole compounds of formula I, such as the …