[HTML][HTML] New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro-and microstructural MRI findings

LB Norbom, L Ferschmann, N Parker, I Agartz… - Progress in …, 2021 - Elsevier
Through dynamic transactional processes between genetic and environmental factors,
childhood and adolescence involve reorganization and optimization of the cerebral cortex …

Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures

J Li, J Seidlitz, J Suckling, F Fan, GJ Ji, Y Meng… - Nature …, 2021 - nature.com
Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation …

Multimodal gradients across mouse cortex

BD Fulcher, JD Murray, V Zerbi… - Proceedings of the …, 2019 - National Acad Sciences
The primate cerebral cortex displays a hierarchy that extends from primary sensorimotor to
association areas, supporting increasingly integrated function underpinned by a gradient of …

Overcoming false-positive gene-category enrichment in the analysis of spatially resolved transcriptomic brain atlas data

BD Fulcher, A Arnatkeviciute, A Fornito - Nature communications, 2021 - nature.com
Transcriptomic atlases have improved our understanding of the correlations between gene-
expression patterns and spatially varying properties of brain structure and function. Gene …

Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders

J Rokicki, T Wolfers, W Nordhøy, N Tesli… - Human brain …, 2021 - Wiley Online Library
The deviation between chronological age and age predicted using brain MRI is a putative
marker of overall brain health. Age prediction based on structural MRI data shows high …

Gene set enrichment for reproducible science: comparison of CERNO and eight other algorithms

J Zyla, M Marczyk, T Domaszewska… - …, 2019 - academic.oup.com
Motivation Analysis of gene set (GS) enrichment is an essential part of functional omics
studies. Here, we complement the established evaluation metrics of GS enrichment …

[HTML][HTML] Imaging transcriptomics: Convergent cellular, transcriptomic, and molecular neuroimaging signatures in the healthy adult human brain

D Martins, A Giacomel, SCR Williams, F Turkheimer… - Cell reports, 2021 - cell.com
The integration of transcriptomic and neuroimaging data," imaging transcriptomics," has
recently emerged to generate hypotheses about potential biological pathways underlying …

Waves of maturation and senescence in micro-structural MRI markers of human cortical myelination over the lifespan

H Grydeland, PE Vértes, F Váša… - Cerebral …, 2019 - academic.oup.com
Seminal human brain histology work has demonstrated developmental waves of
myelination. Here, using a micro-structural magnetic resonance imaging (MRI) marker linked …

[HTML][HTML] Virtual histology of multi-modal magnetic resonance imaging of cerebral cortex in young men

Y Patel, J Shin, M Drakesmith, J Evans, Z Pausova… - NeuroImage, 2020 - Elsevier
Neurobiology underlying inter-regional variations-across the human cerebral cortex-in
measures derived with multi-modal magnetic resonance imaging (MRI) is poorly …

Cortical morphology at birth reflects spatiotemporal patterns of gene expression in the fetal human brain

G Ball, J Seidlitz, J O'Muircheartaigh, R Dimitrova… - PLoS …, 2020 - journals.plos.org
Interruption to gestation through preterm birth can significantly impact cortical development
and have long-lasting adverse effects on neurodevelopmental outcome. We compared …