Autoimmune disease in women: endocrine transition and risk across the lifespan

MK Desai, RD Brinton - Frontiers in endocrinology, 2019 - frontiersin.org
Women have a higher incidence and prevalence of autoimmune diseases than men, and
85% or more patients of multiple autoimmune diseases are female. Women undergo …

Sex effects across the lifespan in women with multiple sclerosis

KM Krysko, JS Graves, R Dobson… - Therapeutic …, 2020 - journals.sagepub.com
Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating central nervous
system disorder that is more common in women, with onset often during reproductive years …

2016 IMS Recommendations on women's midlife health and menopause hormone therapy

RJ Baber, N Panay, A Fenton - Climacteric, 2016 - Taylor & Francis
Abstract The International Menopause Society (IMS) has produced these new 2016
recommendations on women's midlife health and menopause hormone therapy (MHT) to …

Role of oligodendrocyte dysfunction in demyelination, remyelination and neurodegeneration in multiple sclerosis

AO Dulamea - Multiple Sclerosis: Bench to Bedside: Global …, 2017 - Springer
Oligodendrocytes (OLs) are the myelinating cells of the central nervous system (CNS) during
development and throughout adulthood. They result from a complex and well controlled …

Role of sex steroids in β cell function, growth, and survival

F Mauvais-Jarvis - Trends in Endocrinology & Metabolism, 2016 - cell.com
The gonads have long been considered endocrine glands, producing sex steroids such as
estrogens, androgens, and progesterone (P4) for the sole purpose of sexual differentiation …

Estrogen and Alzheimer's disease: Still an attractive topic despite disappointment from early clinical results

S Merlo, SF Spampinato, MA Sortino - European Journal of Pharmacology, 2017 - Elsevier
Since publication of the results of the Women Health Initiative Memory Study demonstrating
that hormone therapy initiated late after menopause increases the risk of dementia in …

Reproductive history and progressive multiple sclerosis risk in women

B Zeydan, EJ Atkinson, DM Weis, CY Smith… - Brain …, 2020 - academic.oup.com
Being a woman is one of the strongest risk factors for multiple sclerosis. The natural
reproductive period from menarche to natural menopause corresponds to the active …

The adaptive immune system in multiple sclerosis: an estrogen-mediated point of view

A Maglione, S Rolla, SFD Mercanti, S Cutrupi… - Cells, 2019 - mdpi.com
Multiple sclerosis (MS) is a chronic central nervous system inflammatory disease that leads
to demyelination and neurodegeneration. The third trimester of pregnancy, which is …

The contribution of oligodendrocytes and oligodendrocyte progenitor cells to central nervous system repair in multiple sclerosis: perspectives for remyelination …

AO Dulamea - Neural regeneration research, 2017 - journals.lww.com
Oligodencrocytes (OLs) are the main glial cells of the central nervous system involved in
myelination of axons. In multiple sclerosis (MS), there is an imbalance between …

Sex hormones as key modulators of the immune response in multiple sclerosis: a review

F Murgia, F Giagnoni, L Lorefice, P Caria, T Dettori… - Biomedicines, 2022 - mdpi.com
Background: A variety of autoimmune diseases, including MS, amplify sex-based
physiological differences in immunological responsiveness. Female MS patients experience …