[HTML][HTML] A narrative review on treatment strategies for neonatal hypoxic ischemic encephalopathy

JM Korf, LD McCullough, V Caretti - Translational Pediatrics, 2023 - ncbi.nlm.nih.gov
Methods We included full articles and book chapters published in English on PubMed with
references to “hypoxic ischemic encephalopathy”,“birth asphyxia”,“therapeutic hypothermia” …

PKN1 Exerts Neurodegenerative Effects in an In Vitro Model of Cerebellar Hypoxic–Ischemic Encephalopathy via Inhibition of AKT/GSK3β Signaling

S Zur Nedden, MS Safari, F Fresser, K Faserl… - Biomolecules, 2023 - mdpi.com
We recently identified protein kinase N1 (PKN1) as a negative gatekeeper of neuronal AKT
protein kinase activity during postnatal cerebellar development. The developing cerebellum …

GluN2B-containing NMDA receptor attenuated neuronal apoptosis in the mouse model of HIBD through inhibiting endoplasmic reticulum stress-activated PERK/eIF2α …

M Wu, S Xu, K Mi, S Yang, Y Xu, J Li, J Chen… - Frontiers in Molecular …, 2024 - frontiersin.org
Introduction Neonatal hypoxic-ischemic brain damage (HIBD) refers to brain damage in
newborns caused by hypoxia and reduced or even stopped cerebral blood flow during the …

Structural and functional effects of C5aR1 antagonism in a rat model of neonatal hypoxic-ischemic encephalopathy

A Saadat, H Pallera, F Lattanzio, D Owens… - Developmental …, 2024 - karger.com
The complement response activates upon reperfusion in neonatal hypoxic-ischemic
encephalopathy (HIE) and contributes to excessive neuroinflammation and worse outcomes …

Fine motor deficits exhibited in rat string-pulling behavior following exposure to sleep fragmentation and deep space radiation

AA Blackwell, JA Tracz, AS Fesshaye… - Experimental Brain …, 2023 - Springer
Deep space flight missions will expose astronauts to multiple stressors, including sleep
fragmentation and space radiation. There is debate over whether sleep disruptions are an …