Reactive oxygen species (ROS) are produced by living cells as normal cellular metabolic
byproduct. Under excessive stress conditions, cells will produce numerous ROS, and the …

Liver transplantation is the ultimate method for treating end-stage liver disease. With the
increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a …

Liver disease causing end organ failure is a growing cause of mortality. In most cases, the
only therapy is liver transplantation. However, liver transplantation is a complex undertaking …

Redox state constitutes an important background of numerous liver disorders. The redox
state participates in the course of inflammatory, metabolic and proliferative liver diseases …

Antibacterial photodynamic therapy (APDT) has drawn increasing attention from the
scientific society for its potential to effectively kill multidrug-resistant pathogenic bacteria and …

The liver metabolizes ethanol through three enzymatic pathways: alcohol dehydrogenase
(ADH), cytochrome p450 (also called MEOS), and catalase. Alcohol dehydrogenase class I …

Aims: Increased fructose consumption predisposes the liver to nonalcoholic fatty liver
disease (NAFLD), but the mechanisms are elusive. Thioredoxin-interacting protein (TXNIP) …

Organ transplantation is undergoing profound changes. Contraindications for donation have
been revised in order to better meet the organ demand. The use of lower-quality organs and …

Non-alcoholic fatty liver disease (NAFLD) is characterised by an excess of hepatic fat that
can progress to steatohepatitis, fibrosis, cirrhosis and hepatocarcinoma. The imbalance …

Hepatic ischemia-reperfusion injury is a major cause of liver transplant failure, and is of
increasing significance due to increased use of expanded criteria livers for transplantation …