Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

Y Zheng, SH Ley, FB Hu - Nature reviews endocrinology, 2018 - nature.com
Globally, the number of people with diabetes mellitus has quadrupled in the past three
decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults …

A clinical update on gestational diabetes mellitus

A Sweeting, J Wong, HR Murphy, GP Ross - Endocrine reviews, 2022 - academic.oup.com
Gestational diabetes mellitus (GDM) traditionally refers to abnormal glucose tolerance with
onset or first recognition during pregnancy. GDM has long been associated with obstetric …

ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents

AS Shah, PS Zeitler, J Wong, AS Pena… - Pediatric …, 2022 - Wiley Online Library
Since the 2018 ISPAD guidelines on this topic, follow‐up of large cohorts from around the
globe have continued informing the current incidence and prevalence of co‐morbidities and …

Risk factors for type 2 diabetes mellitus: an exposure-wide umbrella review of meta-analyses

V Bellou, L Belbasis, I Tzoulaki, E Evangelou - PloS one, 2018 - journals.plos.org
Background Type 2 diabetes mellitus (T2DM) is a global epidemic associated with
increased health expenditure, and low quality of life. Many non-genetic risk factors have …

Racism, xenophobia, and discrimination: mapping pathways to health outcomes

S Selvarajah, SC Maioli, T Abi Deivanayagam… - The Lancet, 2022 - thelancet.com
Despite being globally pervasive, racism, xenophobia, and discrimination are not universally
recognised determinants of health. We challenge widespread beliefs related to the …

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy

A Levin, M Tonelli, J Bonventre, J Coresh, JA Donner… - The Lancet, 2017 - thelancet.com
The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus

A Kautzky-Willer, J Harreiter, G Pacini - Endocrine reviews, 2016 - academic.oup.com
The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

Childhood stunting: a global perspective

M De Onis, F Branca - Maternal & child nutrition, 2016 - Wiley Online Library
Childhood stunting is the best overall indicator of children's well‐being and an accurate
reflection of social inequalities. Stunting is the most prevalent form of child malnutrition with …

Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis

VD D'Agati, A Chagnac, AP De Vries, M Levi… - Nature Reviews …, 2016 - nature.com
The prevalence of obesity-related glomerulopathy is increasing in parallel with the
worldwide obesity epidemic. Glomerular hypertrophy and adaptive focal segmental …

Detecting pleiotropy in Mendelian randomisation studies with summary data and a continuous outcome

FD Greco M, C Minelli, NA Sheehan… - Statistics in …, 2015 - Wiley Online Library
Mendelian randomisation (MR) estimates causal effects of modifiable phenotypes on an
outcome by using genetic variants as instrumental variables, but its validity relies on the …